| The small GTP-binding proteins Rac1 and Cdc42regulate the activity of the JNK/SAPK signaling pathway OA Coso, M Chiariello, JC Yu, H Teramoto, P Crespo, N Xu, T Miki, ... Cell 81 (7), 1137-1146, 1995 | 2141 | 1995 |
| Ras-dependent activation of MAP kinase pathway mediated by G-protein βγ subunits P Crespo, N Xu, WF Simonds, JS Gutkind Nature 369 (6479), 418-420, 1994 | 1082 | 1994 |
| Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product P Crespo, KE Schuebel, AA Ostrom, JS Gutkind, XR Bustelo Nature 385 (6612), 169-172, 1997 | 985 | 1997 |
| Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase γ M Lopez-Ilasaca, P Crespo, PG Pellici, JS Gutkind, R Wetzker Science 275 (5298), 394-397, 1997 | 881 | 1997 |
| Dual Effect of β-Adrenergic Receptors on Mitogen-activated Protein Kinase: EVIDENCE FOR A βγ-DEPENDENT ACTIVATION AND A Gαs-cAMP-MEDIATED INHIBITION (∗) P Crespo, TG Cachero, N Xu, JS Gutkind Journal of Biological Chemistry 270 (42), 25259-25265, 1995 | 279 | 1995 |
| Ras proteins in the control of the cell cycle and cell differentiation P Crespo, J Leon Cellular and Molecular Life Sciences CMLS 57, 1613-1636, 2000 | 248 | 2000 |
| The small GTP-binding protein rho activates c-Jun N-terminal kinases/stress-activated protein kinases in human kidney 293T cells: evidence for a Pak-independent signaling pathway H Teramoto, P Crespo, OA Coso, T Igishi, N Xu, JS Gutkind Journal of Biological Chemistry 271 (42), 25731-25734, 1996 | 235 | 1996 |
| Erk5 participates in neuregulin signal transduction and is constitutively active in breast cancer cells overexpressing ErbB2 A Esparís-Ogando, E Díaz-Rodríguez, JC Montero, L Yuste, P Crespo, ... Molecular and cellular biology 22 (1), 270-285, 2002 | 224 | 2002 |
| Rac-1 dependent stimulation of the JNK/SAPK signaling pathway by Vav. P Crespo, XR Bustelo, DS Aaronson, OA Coso, M López Barahona, ... Oncogene, 1996 | 222 | 1996 |
| Essential role of ERK dimers in the activation of cytoplasmic but not nuclear substrates by ERK-scaffold complexes B Casar, A Pinto, P Crespo Molecular cell 31 (5), 708-721, 2008 | 199 | 2008 |
| Fast regulation of AP-1 activity through interaction of lamin A/C, ERK1/2, and c-Fos at the nuclear envelope JM González, A Navarro-Puche, B Casar, P Crespo, V Andres The Journal of cell biology 183 (4), 653-666, 2008 | 195 | 2008 |
| Phosphorylation of p38 by GRK2 at the docking groove unveils a novel mechanism for inactivating p38MAPK S Peregrin, M Jurado-Pueyo, PM Campos, V Sanz-Moreno, ... Current Biology 16 (20), 2042-2047, 2006 | 165 | 2006 |
| Small molecule inhibition of ERK dimerization prevents tumorigenesis by RAS-ERK pathway oncogenes A Herrero, A Pinto, P Colón-Bolea, B Casar, M Jones, L Agudo-Ibáñez, ... Cancer cell 28 (2), 170-182, 2015 | 157 | 2015 |
| Mutant K-Ras activation of the proapoptotic MST2 pathway is antagonized by wild-type K-Ras D Matallanas, D Romano, F Al-Mulla, E O'Neill, W Al-Ali, P Crespo, ... Molecular cell 44 (6), 893-906, 2011 | 154 | 2011 |
| Distinct utilization of effectors and biological outcomes resulting from site-specific Ras activation: Ras functions in lipid rafts and Golgi complex are dispensable for … D Matallanas, V Sanz-Moreno, I Arozarena, F Calvo, L Agudo-Ibánez, ... Molecular and cellular biology 26 (1), 100-116, 2006 | 153 | 2006 |
| Mechanisms of action of vitamin D in colon cancer G Ferrer-Mayorga, MJ Larriba, P Crespo, A Muñoz The Journal of steroid biochemistry and molecular biology 185, 1-6, 2019 | 151 | 2019 |
| Differences on the inhibitory specificities of H-Ras, K-Ras, and N-Ras (N17) dominant negative mutants are related to their membrane microlocalization D Matallanas, I Arozarena, MT Berciano, DS Aaronson, A Pellicer, ... Journal of Biological Chemistry 278 (7), 4572-4581, 2003 | 148 | 2003 |
| Ras subcellular localization defines extracellular signal-regulated kinase 1 and 2 substrate specificity through distinct utilization of scaffold proteins B Casar, I Arozarena, V Sanz-Moreno, A Pinto, L Agudo-Ibáñez, R Marais, ... Molecular and cellular biology 29 (5), 1338-1353, 2009 | 143 | 2009 |
| Activation of H-Ras in the endoplasmic reticulum by the RasGRF family guanine nucleotide exchange factors I Arozarena, D Matallanas, MT Berciano, V Sanz-Moreno, F Calvo, ... Molecular and cellular biology 24 (4), 1516-1530, 2004 | 122 | 2004 |
| Signaling through transforming G protein-coupled receptors in NIH 3T3 cells involves c-Raf activation. Evidence for a protein kinase C-independent pathway. P Crespo, N Xu, JL Daniotti, J Troppmair, UR Rapp, JS Gutkind Journal of Biological Chemistry 269 (33), 21103-21109, 1994 | 114 | 1994 |
