| Discovery of ARD-69 as a highly potent proteolysis targeting chimera (PROTAC) degrader of androgen receptor (AR) for the treatment of prostate cancer X Han, C Wang, C Qin, W Xiang, E Fernandez-Salas, CY Yang, M Wang, ... Journal of medicinal chemistry 62 (2), 941-964, 2019 | 329 | 2019 |
| Discovery of QCA570 as an exceptionally potent and efficacious proteolysis targeting chimera (PROTAC) degrader of the bromodomain and extra-terminal (BET) proteins capable of … C Qin, Y Hu, B Zhou, E Fernandez-Salas, CY Yang, L Liu, D McEachern, ... Journal of medicinal chemistry 61 (15), 6685-6704, 2018 | 242 | 2018 |
| Iron-Facilitated Direct Oxidative C− H Transformation of Allylarenes or Alkenes to Alkenyl Nitriles C Qin, N Jiao Journal of the American Chemical Society 132 (45), 15893-15895, 2010 | 193 | 2010 |
| Silver-Catalyzed Nitrogenation of Alkynes: A Direct Approach to Nitriles through C C Bond Cleavage. T Shen, T Wang, C Qin, N Jiao Angewandte Chemie 125 (26), 2013 | 181 | 2013 |
| Discovery of highly potent and efficient PROTAC degraders of androgen receptor (AR) by employing weak binding affinity VHL E3 ligase ligands X Han, L Zhao, W Xiang, C Qin, B Miao, T Xu, M Wang, CY Yang, ... Journal of medicinal chemistry 62 (24), 11218-11231, 2019 | 172 | 2019 |
| Ru (ii)-catalyzed intermolecular C–H amidation of weakly coordinating ketones QZ Zheng, YF Liang, C Qin, N Jiao Chemical communications 49 (50), 5654-5656, 2013 | 149 | 2013 |
| Iron-catalyzed CH and CC bond cleavage: a direct approach to amides from simple hydrocarbons. C Qin, W Zhou, F Chen, Y Ou, N Jiao Angewandte Chemie (International ed. in English) 50 (52), 12595-12599, 2011 | 127 | 2011 |
| Small-molecule PROTAC degraders of the Bromodomain and Extra Terminal (BET) proteins—A review CY Yang, C Qin, L Bai, S Wang Drug Discovery Today: Technologies 31, 43-51, 2019 | 107 | 2019 |
| Selective C (sp2)-C (sp) bond cleavage: the nitrogenation of alkynes to amides. C Qin, P Feng, Y Ou, T Shen, T Wang, N Jiao Angewandte Chemie (International ed. in English) 52 (30), 7850-7854, 2013 | 95 | 2013 |
| Discovery of ARD-2585 as an exceptionally potent and orally active PROTAC degrader of androgen receptor for the treatment of advanced prostate cancer W Xiang, L Zhao, X Han, C Qin, B Miao, D McEachern, Y Wang, ... Journal of medicinal chemistry 64 (18), 13487-13509, 2021 | 92 | 2021 |
| Strategies toward discovery of potent and orally bioavailable proteolysis targeting chimera degraders of androgen receptor for the treatment of prostate cancer X Han, L Zhao, W Xiang, C Qin, B Miao, D McEachern, Y Wang, ... Journal of medicinal chemistry 64 (17), 12831-12854, 2021 | 82 | 2021 |
| Implanting Nitrogen into Hydrocarbon Molecules through C H and C C Bond Cleavages: A Direct Approach to Tetrazoles F Chen, C Qin, Y Cui, N Jiao Angewandte Chemie 48 (123), 11689-11693, 2011 | 81 | 2011 |
| Splitting a Substrate into Three Parts: Gold‐Catalyzed Nitrogenation of Alkynes by C C and C C Bond Cleavage C Qin, Y Su, T Shen, X Shi, N Jiao Angewandte Chemie 128 (1), 358-362, 2016 | 79 | 2016 |
| FeCl2-promoted cleavage of the unactivated CC bond of alkylarenes and polystyrene: direct synthesis of arylamines. C Qin, T Shen, C Tang, N Jiao Angewandte Chemie (International ed. in English) 51 (28), 6971-6975, 2012 | 70 | 2012 |
| Oxygenation of Simple Olefins through Selective Allylic C− C Bond Cleavage: A Direct Approach to Cinnamyl Aldehydes J Liu, X Wen, C Qin, X Li, X Luo, A Sun, B Zhu, S Song, N Jiao Angewandte Chemie International Edition 56 (39), 11940-11944, 2017 | 28 | 2017 |
| Iron-facilitated direct oxidative C–H transformation of allyl arenes to alkenyl aldehydes T Wang, SK Xiang, C Qin, JA Ma, LH Zhang, N Jiao Tetrahedron letters 52 (25), 3208-3211, 2011 | 18 | 2011 |
| Discovery of ARD-2051 as a potent and orally efficacious proteolysis targeting chimera (PROTAC) degrader of androgen receptor for the treatment of advanced prostate cancer X Han, L Zhao, W Xiang, B Miao, C Qin, M Wang, T Xu, D McEachern, ... Journal of Medicinal Chemistry 66 (13), 8822-8843, 2023 | 14 | 2023 |
| PROTAC degraders of androgen receptor‐integrated dissolving microneedles for androgenetic alopecia and recrudescence treatment via single topical administration R Wang, T Zhong, Q Bian, S Zhang, X Ma, L Li, Y Xu, Y Gu, A Yuan, W Hu, ... Small Methods 7 (1), 2201293, 2023 | 14 | 2023 |
| Novel sulfonylurea-based NLRP3 inflammasome inhibitor for efficient treatment of nonalcoholic steatohepatitis, endotoxic shock, and colitis Z Li, Y Chen, X Jiang, P Lu, C Wang, Z Li, X Yu, Z Yang, S Ma, S Du, Z Tai, ... Journal of Medicinal Chemistry 66 (18), 12966-12989, 2023 | 6 | 2023 |
| Discovery of BWA-522, a First-in-Class and Orally Bioavailable PROTAC Degrader of the Androgen Receptor Targeting N-Terminal Domain for the Treatment of … B Zhang, C Liu, Z Yang, S Zhang, X Hu, B Li, M Mao, X Wang, Z Li, S Ma, ... Journal of Medicinal Chemistry 66 (16), 11158-11186, 2023 | 6 | 2023 |
