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zardi luciano
zardi luciano
CEO and President sirius-biotech
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Blue silver: a very sensitive colloidal Coomassie G‐250 staining for proteome analysis
G Candiano, M Bruschi, L Musante, L Santucci, GM Ghiggeri, ...
Electrophoresis 25 (9), 1327-1333, 2004
25112004
The fibronectin domain ED-A is crucial for myofibroblastic phenotype induction by transforming growth factor-β1
G Serini, ML Bochaton-Piallat, P Ropraz, A Geinoz, L Borsi, L Zardi, ...
The Journal of cell biology 142 (3), 873-881, 1998
10971998
CIITA-induced MHC class II expression in mammary adenocarcinoma leads to a Th1 polarization of the tumor microenvironment, tumor rejection, and specific antitumor memory
L Mortara, P Castellani, R Meazza, G Tosi, A De Lerma Barbaro, ...
Clinical cancer research 12 (11), 3435-3443, 2006
8092006
Design and use of a phage display library: human antibodies with subnanomolar affinity against a marker of angiogenesis eluted from a two-dimensional gel
A Pini, F Viti, A Santucci, B Carnemolla, L Zardi, P Neri, D Neri
Journal of Biological Chemistry 273 (34), 21769-21776, 1998
6311998
Membrane‐type matrix metalloproteinases 1 and 2 exhibit broad‐spectrum proteolytic capacities comparable to many matrix metalloproteinases
MP D'ortho, H Will, S Atkinson, G Butler, A Messent, J Gavrilovic, B Smith, ...
European journal of biochemistry 250 (3), 751-757, 1997
5621997
The role of the C-terminal domain of human collagenase-3 (MMP-13) in the activation of procollagenase-3, substrate specificity, and tissue inhibitor of metalloproteinase …
V Knäuper, S Cowell, B Smith, C López-Otin, M O'Shea, H Morris, L Zardi, ...
Journal of Biological Chemistry 272 (12), 7608-7616, 1997
4481997
Transformed human cells produce a new fibronectin isoform by preferential alternative splicing of a previously unobserved exon.
L Zardi, B Carnemolla, A Siri, TE Petersen, G Paolella, G Sebastio, ...
The EMBO journal 6 (8), 2337-2342, 1987
4431987
Selective targeting of tumoral vasculature: comparison of different formats of an antibody (L19) to the ED‐B domain of fibronectin
L Borsi, E Balza, M Bestagno, P Castellani, B Carnemolla, A Biro, ...
International journal of cancer 102 (1), 75-85, 2002
4272002
A tumor-associated fibronectin isoform generated by alternative splicing of messenger RNA precursors.
B Carnemolla, E Balza, A Siri, L Zardi, MR Nicotra, A Bigotti, PG Natali
The Journal of cell biology 108 (3), 1139-1148, 1989
4211989
Targeting by affinity–matured recombinant antibody fragments of an angiogenesis associated fibronectin isoform
D Neri, B Carnemolla, A Nissim, A Leprini, G Querzè, E Balza, A Pini, ...
Nature biotechnology 15 (12), 1271-1275, 1997
4001997
Immunoscintigraphic detection of the ED-B domain of fibronectin, a marker of angiogenesis, in patients with cancer
M Santimaria, G Moscatelli, GL Viale, L Giovannoni, G Neri, F Viti, ...
Clinical Cancer Research 9 (2), 571-579, 2003
3972003
The fibronectin isoform containing the ED‐B oncofetal domain: a marker of angiogenesis
P Castellani, G Viale, A Dorcaratto, G Nicolo, J Kaczmarek, G Querze, ...
International journal of cancer 59 (5), 612-618, 1994
3971994
Enhancement of the antitumor properties of interleukin-2 by its targeted delivery to the tumor blood vessel extracellular matrix
B Carnemolla, L Borsi, E Balza, P Castellani, R Meazza, A Berndt, ...
Blood, The Journal of the American Society of Hematology 99 (5), 1659-1665, 2002
3622002
Enhancement of the antitumor activity of interleukin-12 by targeted delivery to neovasculature
C Halin, S Rondini, F Nilsson, A Berndt, H Kosmehl, L Zardi, D Neri
Nature biotechnology 20 (3), 264-269, 2002
3372002
Targeted delivery of tissue factor to the ED-B domain of fibronectin, a marker of angiogenesis, mediates the infarction of solid tumors in mice
F Nilsson, H Kosmehl, L Zardi, D Neri
Cancer research 61 (2), 711-716, 2001
3152001
Selective targeted delivery of TNFα to tumor blood vessels
L Borsi, E Balza, B Carnemolla, F Sassi, P Castellani, A Berndt, ...
Blood 102 (13), 4384-4392, 2003
3122003
Increased binding affinity and valence of recombinant antibody fragments lead to improved targeting of tumoral angiogenesis
F Viti, L Tarli, L Giovannoni, L Zardi, D Neri
Cancer research 59 (2), 347-352, 1999
3121999
Differential expression of the ED sequence-containing form of cellular fibronectin in embryonic and adult human tissues
T Vartio, L Laitinen, O Närvänen, M Cutolo, LE Thornell, L Zardi, I Virtanen
Journal of cell science 88 (4), 419-430, 1987
2881987
Fibronectin as target for tumor therapy
M Kaspar, L Zardi, D Neri
International journal of cancer 118 (6), 1331-1339, 2006
2852006
The activation of ProMMP-2 (gelatinase A) by HT1080 fibrosarcoma cells is promoted by culture on a fibronectin substrate and is concomitant with an increase in processing of …
H Stanton, J Gavrilovic, SJ Atkinson, MP d’Ortho, KM Yamada, L Zardi, ...
Journal of cell science 111 (18), 2789-2798, 1998
2761998
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