| Raf family kinases: old dogs have learned new tricks D Matallanas, M Birtwistle, D Romano, A Zebisch, J Rauch, ... Genes & cancer 2 (3), 232-260, 2011 | 469 | 2011 |
| The library of integrated network-based cellular signatures NIH program: system-level cataloging of human cells response to perturbations AB Keenan, SL Jenkins, KM Jagodnik, S Koplev, E He, D Torre, Z Wang, ... Cell systems 6 (1), 13-24, 2018 | 414 | 2018 |
| Cell fate decisions are specified by the dynamic ERK interactome A Von Kriegsheim, D Baiocchi, M Birtwistle, D Sumpton, W Bienvenut, ... Nature cell biology 11 (12), 1458-1464, 2009 | 354 | 2009 |
| Critical role of histone turnover in neuronal transcription and plasticity I Maze, W Wenderski, KM Noh, RC Bagot, N Tzavaras, I Purushothaman, ... Neuron 87 (1), 77-94, 2015 | 317 | 2015 |
| Ligand‐dependent responses of the ErbB signaling network: experimental and modeling analyses MR Birtwistle, M Hatakeyama, N Yumoto, BA Ogunnaike, JB Hoek, ... Molecular systems biology 3 (1), 144, 2007 | 301 | 2007 |
| The mammalian MAPK/ERK pathway exhibits properties of a negative feedback amplifier OE Sturm, R Orton, J Grindlay, M Birtwistle, V Vyshemirsky, D Gilbert, ... Science signaling 3 (153), ra90-ra90, 2010 | 297 | 2010 |
| Ligand-specific c-Fos expression emerges from the spatiotemporal control of ErbB network dynamics T Nakakuki, MR Birtwistle, Y Saeki, N Yumoto, K Ide, T Nagashima, ... Cell 141 (5), 884-896, 2010 | 276 | 2010 |
| Evaluating strategies to normalise biological replicates of Western blot data A Degasperi, MR Birtwistle, N Volinsky, J Rauch, W Kolch, ... PloS one 9 (1), e87293, 2014 | 233 | 2014 |
| Bistability in the Rac1, PAK, and RhoA signaling network drives actin cytoskeleton dynamics and cell motility switches KM Byrne, N Monsefi, JC Dawson, A Degasperi, JC Bukowski-Wills, ... Cell systems 2 (1), 38-48, 2016 | 180 | 2016 |
| A multi-center study on the reproducibility of drug-response assays in mammalian cell lines M Niepel, M Hafner, CE Mills, K Subramanian, EH Williams, M Chung, ... Cell systems 9 (1), 35-48. e5, 2019 | 131 | 2019 |
| Novel somatic mutations to PI3K pathway genes in metastatic melanoma AY Shull, A Latham-Schwark, P Ramasamy, K Leskoske, D Oroian, ... Public Library of Science 7 (8), e43369, 2012 | 113 | 2012 |
| NFκB and HIF display synergistic behaviour during hypoxic inflammation U Bruning, SF Fitzpatrick, T Frank, M Birtwistle, CT Taylor, A Cheong Cellular and Molecular Life Sciences 69, 1319-1329, 2012 | 100 | 2012 |
| Four‐dimensional dynamics of MAPK information‐processing systems BN Kholodenko, MR Birtwistle Wiley Interdisciplinary Reviews: Systems Biology and Medicine 1 (1), 28-44, 2009 | 99 | 2009 |
| Emergence of bimodal cell population responses from the interplay between analog single-cell signaling and protein expression noise MR Birtwistle, J Rauch, A Kiyatkin, E Aksamitiene, M Dobrzyński, JB Hoek, ... BMC systems biology 6, 1-12, 2012 | 97 | 2012 |
| ERK2 drives tumour cell migration in three-dimensional microenvironments by suppressing expression of Rab17 and liprin-β2 A von Thun, M Birtwistle, G Kalna, J Grindlay, D Strachan, W Kolch, ... Journal of cell science 125 (6), 1465-1477, 2012 | 84 | 2012 |
| Drug response consistency in CCLE and CGP M Bouhaddou, MS DiStefano, EA Riesel, E Carrasco, HY Holzapfel, ... Nature 540 (7631), E9-E10, 2016 | 80 | 2016 |
| Cell size assays for mass cytometry AD Stern, AH Rahman, MR Birtwistle Cytometry Part A 91 (1), 14-24, 2017 | 69 | 2017 |
| A comparison of mRNA sequencing with random primed and 3′-directed libraries Y Xiong, M Soumillon, J Wu, J Hansen, B Hu, JG Van Hasselt, ... Scientific reports 7 (1), 14626, 2017 | 66 | 2017 |
| A mechanistic pan-cancer pathway model informed by multi-omics data interprets stochastic cell fate responses to drugs and mitogens M Bouhaddou, AM Barrette, AD Stern, RJ Koch, MS DiStefano, EA Riesel, ... PLoS computational biology 14 (3), e1005985, 2018 | 62 | 2018 |
| Endocytosis and signalling: a meeting with mathematics MR Birtwistle, BN Kholodenko Molecular oncology 3 (4), 308-320, 2009 | 49 | 2009 |
Boris KholodenkoProfessor of Systems Biology, University College DublinBestätigte E-Mail-Adresse bei ucd.ie
