Le Chen
Le Chen
Assistant Research Professor of Cardiology, University of California, Davis
Verified email at
Cited by
Cited by
Mitochondrial OPA1, apoptosis, and heart failure
L Chen, Q Gong, JP Stice, AA Knowlton
Cardiovascular research 84 (1), 91-99, 2009
Cardiac myocyte exosomes: stability, HSP60, and proteomics
ZA Malik, KS Kott, AJ Poe, T Kuo, L Chen, KW Ferrara, AA Knowlton
American Journal of Physiology-Heart and Circulatory Physiology 304 (7 …, 2013
OPA 1 Mutation and Late‐Onset Cardiomyopathy: Mitochondrial Dysfunction and mtDNA Instability
L Chen, T Liu, A Tran, X Lu, AA Tomilov, V Davies, G Cortopassi, ...
Journal of the American Heart Association 1 (5), e003012, 2012
Extracellular heat shock protein 60, cardiac myocytes, and apoptosis
SC Kim, JP Stice, L Chen, JS Jung, S Gupta, Y Wang, G Baumgarten, ...
Circulation research 105 (12), 1186-1195, 2009
Hyperamylinemia contributes to cardiac dysfunction in obesity and diabetes: a study in humans and rats
S Despa, KB Margulies, LE Chen, AA Knowlton, PJ Havel, H Taegtmeyer, ...
Circulation research 110 (4), 598-608, 2012
Mitochondrial dynamics in heart failure
L Chen, AA Knowlton
Congestive heart failure 17 (6), 257-261, 2011
Intermittent high altitude hypoxia inhibits opening of mitochondrial permeability transition pores against reperfusion injury
WZ Zhu, Y Xie, L Chen, HT Yang, ZN Zhou
Journal of molecular and cellular cardiology 40 (1), 96-106, 2006
Intermittent hypoxia protects cardiomyocytes against ischemia-reperfusion injury-induced alterations in Ca2+ homeostasis and contraction via the sarcoplasmic reticulum and Na+ …
L Chen, XY Lu, J Li, JD Fu, ZN Zhou, HT Yang
American Journal of Physiology-Cell Physiology 290 (4), C1221-C1229, 2006
Crucial role of the sarcoplasmic reticulum in the developmental regulation of Ca2+ transients and contraction in cardiomyocytes derived from embryonic stem cells
JD Fu, J Li, D Tweedie, HM Yu, L Chen, R Wang, DR Riordon, SA Brugh, ...
The FASEB Journal 20 (1), 181-183, 2006
Cardiac myocyte Z-line calmodulin is mainly RyR2-bound, and reduction is arrhythmogenic and occurs in heart failure
Y Yang, T Guo, T Oda, A Chakraborty, L Chen, H Uchinoumi, ...
Circulation research 114 (2), 295-306, 2014
Overexpression of heat shock protein 27 protects against ischaemia/reperfusion-induced cardiac dysfunction via stabilization of troponin I and T
XY Lu, L Chen, XL Cai, HT Yang
Cardiovascular research 79 (3), 500-508, 2008
17β-Estradiol, aging, inflammation, and the stress response in the female heart
JP Stice, L Chen, SC Kim, JS Jung, AL Tran, TT Liu, AA Knowlton
Endocrinology 152 (4), 1589-1598, 2011
Mitochondria and heart failure: new insights into an energetic problem
L Chen, AA Knowlton
Minerva cardioangiologica 58 (2), 213, 2010
Heart failure and mitochondrial dysfunction: the role of mitochondrial fission/fusion abnormalities and new therapeutic strategies
AA Knowlton, L Chen, ZA Malik
Journal of cardiovascular pharmacology 63 (3), 196-206, 2014
Regulation of heat shock protein 60 and 72 expression in the failing heart
Y Wang, L Chen, N Hagiwara, AA Knowlton
Journal of molecular and cellular cardiology 48 (2), 360-366, 2010
Role of dual-site phospholamban phosphorylation in intermittent hypoxia-induced cardioprotection against ischemia-reperfusion injury
Y Xie, Y Zhu, WZ Zhu, L Chen, ZN Zhou, WJ Yuan, HT Yang
American Journal of Physiology-Heart and Circulatory Physiology 288 (6 …, 2005
Activation of α1B-adrenoceptors alleviates ischemia/reperfusion injury by limitation of mitochondrial Ca2+ overload in cardiomyocytes
H Gao, L Chen, HT Yang
Cardiovascular research 75 (3), 584-595, 2007
Intermittent high altitude hypoxia protects the heart against lethal Ca2+ overload injury
Y Xie, WZ Zhu, Y Zhu, L Chen, ZN Zhou, HT Yang
Life sciences 76 (5), 559-572, 2004
Mitochondrial proteome remodeling in ischemic heart failure
T Liu, L Chen, E Kim, D Tran, BS Phinney, AA Knowlton
Life sciences 101 (1-2), 27-36, 2014
陈爱莲, 朱博勤, 陈利顶, 吴艳华, 孙然好
应用生态学报, 1120-1128, 2010
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