Mapping neutralizing and immunodominant sites on the SARS-CoV-2 spike receptor-binding domain by structure-guided high-resolution serology L Piccoli, YJ Park, MA Tortorici, N Czudnochowski, AC Walls, ... Cell 183 (4), 1024-1042. e21, 2020 | 1426 | 2020 |
Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity EC Thomson, LE Rosen, JG Shepherd, R Spreafico, A da Silva Filipe, ... Cell 184 (5), 1171-1187. e20, 2021 | 594 | 2021 |
Structural basis of SARS-CoV-2 Omicron immune evasion and receptor engagement M McCallum, N Czudnochowski, LE Rosen, SK Zepeda, JE Bowen, ... Science 375 (6583), 864-868, 2022 | 508 | 2022 |
SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape TN Starr, N Czudnochowski, Z Liu, F Zatta, YJ Park, A Addetia, D Pinto, ... Nature 597 (7874), 97-102, 2021 | 453 | 2021 |
The structural basis of pathogenic subgenomic flavivirus RNA (sfRNA) production EG Chapman, DA Costantino, JL Rabe, SL Moon, J Wilusz, JC Nix, ... Science 344 (6181), 307-310, 2014 | 286 | 2014 |
Zika virus produces noncoding RNAs using a multi-pseudoknot structure that confounds a cellular exonuclease BM Akiyama, HM Laurence, AR Massey, DA Costantino, X Xie, Y Yang, ... Science 354 (6316), 1148-1152, 2016 | 263 | 2016 |
Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35 DW Leung, KC Prins, DM Borek, M Farahbakhsh, JAM Tufariello, ... Nature structural & molecular biology 17 (2), 165-172, 2010 | 234 | 2010 |
Structure of the Ebola VP35 interferon inhibitory domain DW Leung, ND Ginder, DB Fulton, J Nix, CF Basler, RB Honzatko, ... Proceedings of the National Academy of Sciences 106 (2), 411-416, 2009 | 176 | 2009 |
Interactions between the quality control ubiquitin ligase CHIP and ubiquitin conjugating enzymes Z Xu, E Kohli, KI Devlin, M Bold, JC Nix, S Misra BMC structural biology 8, 1-13, 2008 | 146 | 2008 |
Functional requirements for specific ligand recognition by a biotin-binding RNA pseudoknot C Wilson, J Nix, J Szostak Biochemistry 37 (41), 14410-14419, 1998 | 146 | 1998 |
The structural basis for molecular recognition by the vitamin B12 RNA aptamer D Sussman, JC Nix, C Wilson Nature structural biology 7 (1), 53-57, 2000 | 143 | 2000 |
Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE). Part I: Structure guided discovery and optimization of dual targeting agents with potent, broad … LW Tari, M Trzoss, DC Bensen, X Li, Z Chen, T Lam, J Zhang, ... Bioorganic & medicinal chemistry letters 23 (5), 1529-1536, 2013 | 121 | 2013 |
Investigating the impact of polymer functional groups on the stability and activity of lysozyme–polymer conjugates M Lucius, R Falatach, C McGlone, K Makaroff, A Danielson, C Williams, ... Biomacromolecules 17 (3), 1123-1134, 2016 | 110 | 2016 |
Tricyclic GyrB/ParE (TriBE) inhibitors: a new class of broad-spectrum dual-targeting antibacterial agents LW Tari, X Li, M Trzoss, DC Bensen, Z Chen, T Lam, J Zhang, SJ Lee, ... PloS one 8 (12), e84409, 2013 | 110 | 2013 |
Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2 L Zhang, T Xu, C Maeder, LO Bud, J Shanks, J Nix, C Guthrie, JA Pleiss, ... Nature structural & molecular biology 16 (7), 731-739, 2009 | 110 | 2009 |
A bipartite interaction between Hsp70 and CHIP regulates ubiquitination of chaperoned client proteins H Zhang, J Amick, R Chakravarti, S Santarriaga, S Schlanger, C McGlone, ... Structure 23 (3), 472-482, 2015 | 109 | 2015 |
Structural analysis and DNA binding of the HMG domains of the human mitochondrial transcription factor A TA Gangelhoff, PS Mungalachetty, JC Nix, MEA Churchill Nucleic acids research 37 (10), 3153-3164, 2009 | 109 | 2009 |
The circulating SARS-CoV-2 spike variant N439K maintains fitness while evading antibody-mediated immunity EC Thomson, LE Rosen, JG Shepherd, R Spreafico, A da Silva Filipe, ... BioRxiv, 2020.11. 04.355842, 2020 | 107 | 2020 |
Structural basis of nucleotide exchange and client binding by the Hsp70 cochaperone Bag2 Z Xu, RC Page, MM Gomes, E Kohli, JC Nix, AB Herr, C Patterson, ... Nature structural & molecular biology 15 (12), 1309-1317, 2008 | 105 | 2008 |
Evaluation of integrin αvβ6 cystine knot PET tracers to detect cancer and idiopathic pulmonary fibrosis RH Kimura, L Wang, B Shen, L Huo, W Tummers, FV Filipp, HH Guo, ... Nature communications 10 (1), 4673, 2019 | 99 | 2019 |