| Single-nucleotide human disease mutation inactivates a blood-regenerative GATA2 enhancer AA Soukup, Y Zheng, C Mehta, J Wu, P Liu, M Cao, I Hofmann, Y Zhou, ... The Journal of clinical investigation 129 (3), 1180-1192, 2019 | 53 | 2019 |
| Loss of wild-type Kras promotes activation of all Ras isoforms in oncogenic Kras-induced leukemogenesis G Kong, YI Chang, A Damnernsawad, X You, J Du, EA Ranheim, W Lee, ... Leukemia 30 (7), 1542-1551, 2016 | 46 | 2016 |
| Loss of Dnmt3a and endogenous KrasG12D/+ cooperate to regulate hematopoietic stem and progenitor cell functions in leukemogenesis YI Chang, X You, G Kong, EA Ranheim, J Wang, J Du, Y Liu, Y Zhou, ... Leukemia 29 (9), 1847-1856, 2015 | 44 | 2015 |
| Unique dependence on Sos1 in KrasG12D-induced leukemogenesis X You, G Kong, EA Ranheim, D Yang, Y Zhou, J Zhang Blood, The Journal of the American Society of Hematology 132 (24), 2575-2579, 2018 | 39 | 2018 |
| Kras is Required for Adult Hematopoiesis A Damnernsawad, G Kong, Z Wen, Y Liu, A Rajagopalan, X You, J Wang, ... Stem cells 34 (7), 1859-1871, 2016 | 39 | 2016 |
| Expression of NrasQ61R and MYC transgene in germinal center B cells induces a highly malignant multiple myeloma in mice Z Wen, A Rajagopalan, ED Flietner, G Yun, M Chesi, Q Furumo, RT Burns, ... Blood, The Journal of the American Society of Hematology 137 (1), 61-74, 2021 | 32 | 2021 |
| p53 −/− synergizes with enhanced NrasG12D signaling to transform megakaryocyte-erythroid progenitors in acute myeloid leukemia J Zhang, G Kong, A Rajagopalan, L Lu, J Song, M Hussaini, X Zhang, ... Blood, The Journal of the American Society of Hematology 129 (3), 358-370, 2017 | 31 | 2017 |
| Asxl1 loss cooperates with oncogenic Nras in mice to reprogram the immune microenvironment and drive leukemic transformation X You, F Liu, M Binder, A Vedder, T Lasho, Z Wen, X Gao, E Flietner, ... Blood, The Journal of the American Society of Hematology 139 (7), 1066-1079, 2022 | 27 | 2022 |
| The ability of endogenous Nras oncogenes to initiate leukemia is codon-dependent G Kong, YI Chang, X You, EA Ranheim, Y Zhou, CE Burd, J Zhang Leukemia 30 (9), 1935-1938, 2016 | 26 | 2016 |
| Downregulating Notch counteracts KrasG12D-induced ERK activation and oxidative phosphorylation in myeloproliferative neoplasm G Kong, X You, Z Wen, YI Chang, S Qian, EA Ranheim, C Letson, ... Leukemia 33 (3), 671-685, 2019 | 16 | 2019 |
| Ponatinib sensitizes myeloma cells to MEK inhibition in the high-risk VQ model E Flietner, Z Wen, A Rajagopalan, O Jung, L Watkins, J Wiesner, X You, ... Scientific Reports 12 (1), 10616, 2022 | 7 | 2022 |
| Gata2 −77 enhancer regulates adult hematopoietic stem cell survival X You, YI Chang, G Kong, EA Ranheim, Y Zhou, KD Johnson, C Mehta, ... Leukemia 35 (3), 901-905, 2021 | 7 | 2021 |
| Embryonic Expression of NrasG 12 D Leads to Embryonic Lethality and Cardiac Defects X You, MJ Ryu, E Cho, Y Sang, A Damnernsawad, Y Zhou, Y Liu, J Zhang, ... Frontiers in Cell and Developmental Biology 9, 633661, 2021 | 6 | 2021 |
| Gata2 +9.5 enhancer regulates adult hematopoietic stem cell self-renewal and T-cell development X You, Y Zhou, YI Chang, G Kong, EA Ranheim, KD Johnson, AA Soukup, ... Blood advances 6 (4), 1095-1099, 2022 | 5 | 2022 |
| Nras Q61R/+ and Kras−/− cooperate to downregulate Rasgrp1 and promote lympho-myeloid leukemia in early T-cell precursors Z Wen, G Yun, A Hebert, G Kong, EA Ranheim, R Finn, A Rajagoplan, ... Blood, The Journal of the American Society of Hematology 137 (23), 3259-3271, 2021 | 5 | 2021 |
| Mice expressing MYC and NrasQ61R in germinal center B cells develop highly aggressive multiple myeloma A Rajagopalan, Z Wen, Q Furumo, EA Ranheim, R Finn, E Flietner, G Yun, ... Blood 132, 1006, 2018 | 4 | 2018 |
| A gain-of-function p53 mutant synergizes with oncogenic NRAS to promote acute myeloid leukemia in mice A Rajagopalan, Y Feng, MB Gayatri, EA Ranheim, T Klungness, ... The Journal of Clinical Investigation 133 (24), 2023 | 2 | 2023 |
| Molecular characterization stratifies VQ myeloma cells into two clusters with distinct risk signatures and drug responses E Flietner, M Yu, G Poudel, AJ Veltri, Y Zhou, A Rajagopalan, Y Feng, ... Oncogene 42 (21), 1751-1762, 2023 | 1 | 2023 |
| Loss of Asxl1 cooperates with oncogenic Nras to drive CMML progression X You, Z Wen, G Kong, A Rajagopalan, EA Ranheim, Y Zhou, MM Patnaik, ... Blood 134, 3790, 2019 | 1 | 2019 |
| Systemic Notch downregulation promotes KrasG12D‐induced myeloproliferative neoplasm X You, Z Wen, YI Chang, EA Ranheim, Y Zhou, L Zhou, G Kong, J Zhang British Journal of Haematology 186 (3), e52-e56, 2019 | 1 | 2019 |
XIAONA YOUUW-MadisonVerified email at wisc.edu
