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Karen Gooch
Karen Gooch
Verified email at phe.gov.uk
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Cited by
Cited by
Year
Evaluation of vaccines in the EU TB Vaccine Cluster using a guinea pig aerosol infection model of tuberculosis
A Williams, GJ Hatch, SO Clark, KE Gooch, KA Hatch, GA Hall, K Huygen, ...
Tuberculosis 85 (1-2), 29-38, 2005
2082005
Dose-dependent response to infection with SARS-CoV-2 in the ferret model and evidence of protective immunity
KA Ryan, KR Bewley, SA Fotheringham, GS Slack, P Brown, Y Hall, ...
Nature communications 12 (1), 81, 2021
1612021
Establishment of an aerosol challenge model of tuberculosis in rhesus macaques and an evaluation of endpoints for vaccine testing
SA Sharpe, H McShane, MJ Dennis, RJ Basaraba, F Gleeson, G Hall, ...
Clinical and Vaccine Immunology 17 (8), 1170-1182, 2010
1502010
Metagenomic nanopore sequencing of influenza virus direct from clinical respiratory samples
K Lewandowski, Y Xu, ST Pullan, SF Lumley, D Foster, N Sanderson, ...
Journal of clinical microbiology 58 (1), 10.1128/jcm. 00963-19, 2019
1452019
Safety and immunogenicity of concomitant administration of COVID-19 vaccines (ChAdOx1 or BNT162b2) with seasonal influenza vaccines in adults in the UK (ComFluCOV): a …
R Lazarus, S Baos, H Cappel-Porter, A Carson-Stevens, M Clout, ...
The Lancet 398 (10318), 2277-2287, 2021
1312021
Evaluation of the safety and immunogenicity of a candidate tuberculosis vaccine, MVA85A, delivered by aerosol to the lungs of macaques
AD White, L Sibley, MJ Dennis, K Gooch, G Betts, N Edwards, ...
Clinical and Vaccine Immunology 20 (5), 663-672, 2013
1222013
Comparison of rhesus and cynomolgus macaques as an infection model for COVID-19
FJ Salguero, AD White, GS Slack, SA Fotheringham, KR Bewley, ...
Nature Communications 12 (1), 1260, 2021
1212021
Determination of lesion volume by MRI and stereology in a macaque model of tuberculosis
SA Sharpe, E Eschelbach, RJ Basaraba, F Gleeson, GA Hall, A McIntyre, ...
Tuberculosis 89 (6), 405-416, 2009
792009
Selection of novel TB vaccine candidates and their evaluation as DNA vaccines against aerosol challenge
J Vipond, R Vipond, E Allen-Vercoe, SO Clark, GJ Hatch, KE Gooch, ...
Vaccine 24 (37-39), 6340-6350, 2006
492006
mRNA vaccine CVnCoV protects non-human primates from SARS-CoV-2 challenge infection
S Rauch, K Gooch, Y Hall, FJ Salguero, MJ Dennis, FV Gleeson, D Harris, ...
Biorxiv, 2020.12. 23.424138, 2020
472020
Dose-dependent response to infection with SARS-CoV-2 in the ferret model: evidence of protection to re-challenge
KA Ryan, KR Bewley, SA Fotheringham, P Brown, Y Hall, AC Marriott, ...
BioRxiv, 2020.05. 29.123810, 2020
422020
Differences in monocyte: lymphocyte ratio and Tuberculosis disease progression in genetically distinct populations of macaques
L Sibley, K Gooch, A Wareham, S Gray, A Chancellor, S Dowall, S Bate, ...
Scientific reports 9 (1), 3340, 2019
342019
Heterosubtypic cross-protection correlates with cross-reactive interferon-gamma-secreting lymphocytes in the ferret model of influenza
KE Gooch, AC Marriott, KA Ryan, P Yeates, GS Slack, PJ Brown, ...
Scientific reports 9 (1), 2617, 2019
282019
An aerosol challenge model of tuberculosis in Mauritian cynomolgus macaques
SA Sharpe, AD White, L Sibley, F Gleeson, GA Hall, RJ Basaraba, ...
PLoS One 12 (3), e0171906, 2017
282017
Cellular immune response to human influenza viruses differs between H1N1 and H3N2 subtypes in the ferret lung
KA Ryan, GS Slack, AC Marriott, JA Kane, CJ Whittaker, NJ Silman, ...
PloS one 13 (9), e0202675, 2018
272018
Influenza A virus challenge models in cynomolgus macaques using the authentic inhaled aerosol and intra-nasal routes of infection
AC Marriott, M Dennis, JA Kane, KE Gooch, G Hatch, S Sharpe, ...
PLoS One 11 (6), e0157887, 2016
242016
ChAdOx1 nCoV-19 protection against SARS-CoV-2 in rhesus macaque and ferret challenge models
T Lambe, AJ Spencer, KM Thomas, KE Gooch, S Thomas, AD White, ...
Communications biology 4 (1), 915, 2021
202021
Immunological and pathological outcomes of SARS-CoV-2 challenge following formalin-inactivated vaccine in ferrets and rhesus macaques
KR Bewley, K Gooch, KM Thomas, S Longet, N Wiblin, L Hunter, K Chan, ...
Science advances 7 (37), eabg7996, 2021
192021
One or two dose regimen of the SARS-CoV-2 synthetic DNA vaccine INO-4800 protects against respiratory tract disease burden in nonhuman primate challenge model
KE Gooch, TRF Smith, FJ Salguero, SA Fotheringham, RJ Watson, ...
Vaccine 39 (34), 4885-4894, 2021
192021
Influence of aerosol delivered BCG vaccination on immunological and disease parameters following SARS-CoV-2 challenge in rhesus macaques
AD White, L Sibley, C Sarfas, AL Morrison, K Bewley, C Churchward, ...
Frontiers in immunology 12, 801799, 2022
182022
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