Cross-talk between mitogenic Ras/MAPK and survival PI3K/Akt pathways: a fine balance E Aksamitiene, A Kiyatkin, BN Kholodenko Biochemical Society Transactions 40 (1), 139-146, 2012 | 566 | 2012 |
Untangling the wires: a strategy to trace functional interactions in signaling and gene networks BN Kholodenko, A Kiyatkin, FJ Bruggeman, E Sontag, HV Westerhoff, ... Proceedings of the National Academy of Sciences 99 (20), 12841-12846, 2002 | 504 | 2002 |
Crystallographic structure and functional interpretation of the cytoplasmic domain of erythrocyte membrane band 3 D Zhang, A Kiyatkin, JT Bolin, PS Low Blood, The Journal of the American Society of Hematology 96 (9), 2925-2933, 2000 | 382 | 2000 |
EGFR ligands differentially stabilize receptor dimers to specify signaling kinetics DM Freed, NJ Bessman, A Kiyatkin, E Salazar-Cavazos, PO Byrne, ... Cell 171 (3), 683-695. e18, 2017 | 356 | 2017 |
Systems‐level interactions between insulin–EGF networks amplify mitogenic signaling N Borisov, E Aksamitiene, A Kiyatkin, S Legewie, J Berkhout, T Maiwald, ... Molecular systems biology 5 (1), 256, 2009 | 279 | 2009 |
Scaffolding protein Grb2-associated binder 1 sustains epidermal growth factor-induced mitogenic and survival signaling by multiple positive feedback loops A Kiyatkin, E Aksamitiene, NI Markevich, NM Borisov, JB Hoek, ... Journal of biological chemistry 281 (29), 19925-19938, 2006 | 243 | 2006 |
Inferring dynamic architecture of cellular networks using time series of gene expression, protein and metabolite data E Sontag, A Kiyatkin, BN Kholodenko Bioinformatics 20 (12), 1877-1886, 2004 | 229 | 2004 |
Immunogenicity, efficacy, safety, and mechanism of action of epitope vaccine (Lu AF20513) for Alzheimer's disease: prelude to a clinical trial H Davtyan, A Ghochikyan, I Petrushina, A Hovakimyan, A Davtyan, ... Journal of Neuroscience 33 (11), 4923-4934, 2013 | 189 | 2013 |
Bistability in the Rac1, PAK, and RhoA signaling network drives actin cytoskeleton dynamics and cell motility switches KM Byrne, N Monsefi, JC Dawson, A Degasperi, JC Bukowski-Wills, ... Cell systems 2 (1), 38-48, 2016 | 182 | 2016 |
Kinetochore kinesin CENP-E is a processive bi-directional tracker of dynamic microtubule tips N Gudimchuk, B Vitre, Y Kim, A Kiyatkin, DW Cleveland, FI Ataullakhanov, ... Nature cell biology 15 (9), 1079-1088, 2013 | 159 | 2013 |
Oscillations and waves in metal-ion-catalyzed bromate oscillating reactions in highly oxidized states IRE Anatol M. Zhabotinsky, Frank Buchholtz, Anatol B. Kiyatkin J. Phys. Chem. 97 (29), 7578-7584, 1993 | 137 | 1993 |
PI3K/Akt-sensitive MEK-independent compensatory circuit of ERK activation in ER-positive PI3K-mutant T47D breast cancer cells E Aksamitiene, BN Kholodenko, W Kolch, JB Hoek, A Kiyatkin Cellular signalling 22 (9), 1369-1378, 2010 | 130 | 2010 |
The dark side of cell signaling: positive roles for negative regulators MA Lemmon, DM Freed, J Schlessinger, A Kiyatkin Cell 164 (6), 1172-1184, 2016 | 127 | 2016 |
Anti-Aβ1–11 antibody binds to different β-amyloid species, inhibits fibril formation, and disaggregates preformed fibrils but not the most toxic oligomers G Mamikonyan, M Necula, M Mkrtichyan, A Ghochikyan, I Petrushina, ... Journal of Biological Chemistry 282 (31), 22376-22386, 2007 | 123 | 2007 |
Prolactin-stimulated activation of ERK1/2 mitogen-activated protein kinases is controlled by PI3-kinase/Rac/PAK signaling pathway in breast cancer cells E Aksamitiene, S Achanta, W Kolch, BN Kholodenko, JB Hoek, A Kiyatkin Cellular signalling 23 (11), 1794-1805, 2011 | 122 | 2011 |
Prostaglandin E2 stimulates a Ca2+-dependent K+ channel in human erythrocytes and alters cell volume and filterability Q Li, V Jungmann, A Kiyatkin, PS Low Journal of biological chemistry 271 (31), 18651-18656, 1996 | 119 | 1996 |
Temperature dependence of the epidermal growth factor receptor signaling network can be accounted for by a kinetic model G Moehren, N Markevich, O Demin, A Kiyatkin, I Goryanin, JB Hoek, ... Biochemistry 41 (1), 306-320, 2002 | 105 | 2002 |
Emergence of bimodal cell population responses from the interplay between analog single-cell signaling and protein expression noise MR Birtwistle, J Rauch, A Kiyatkin, E Aksamitiene, M Dobrzyński, JB Hoek, ... BMC systems biology 6, 1-12, 2012 | 97 | 2012 |
Signal processing at the Ras circuit: what shapes Ras activation patterns? NI Markevich, G Moehren, OV Demin, A Kiyatkin, JB Hoek, ... Systems Biology 1 (1), 104-113, 2004 | 84 | 2004 |
Glioblastoma mutations alter EGFR dimer structure to prevent ligand bias C Hu, CA Leche, A Kiyatkin, Z Yu, SE Stayrook, KM Ferguson, ... Nature 602 (7897), 518-522, 2022 | 64 | 2022 |