Genetically altered expression of spermidine/spermine N1-acetyltransferase affects fat metabolism in mice via acetyl-CoA J Jell, S Merali, ML Hensen, R Mazurchuk, JA Spernyak, P Diegelman, ... Journal of Biological Chemistry 282 (11), 8404-8413, 2007 | 152 | 2007 |
Peroxiredoxin 1 controls prostate cancer growth through Toll-like receptor 4–dependent regulation of tumor vasculature JR Riddell, W Bshara, MT Moser, JA Spernyak, BA Foster, SO Gollnick Cancer research 71 (5), 1637-1646, 2011 | 151 | 2011 |
Iron (II) paraCEST MRI contrast agents SJ Dorazio, PB Tsitovich, KE Siters, JA Spernyak, JR Morrow Journal of the American Chemical Society 133 (36), 14154-14156, 2011 | 142 | 2011 |
Mild elevation of body temperature reduces tumor interstitial fluid pressure and hypoxia and enhances efficacy of radiotherapy in murine tumor models A Sen, ML Capitano, JA Spernyak, JT Schueckler, S Thomas, AK Singh, ... Cancer research 71 (11), 3872-3880, 2011 | 134 | 2011 |
A redox-activated MRI contrast agent that switches between paramagnetic and diamagnetic states PB Tsitovich, JA Spernyak, JR Morrow Angewandte Chemie (International ed. in English) 52 (52), 13997, 2013 | 109 | 2013 |
The NiCEST approach: nickel (II) paraCEST MRI contrast agents AO Olatunde, SJ Dorazio, JA Spernyak, JR Morrow Journal of the American Chemical Society 134 (45), 18503-18505, 2012 | 101 | 2012 |
CoCEST: cobalt (II) amide-appended paraCEST MRI contrast agents SJ Dorazio, AO Olatunde, JA Spernyak, JR Morrow Chemical Communications 49 (85), 10025-10027, 2013 | 94 | 2013 |
Chlorophyll-a analogues conjugated with aminobenzyl-DTPA as potential bifunctional agents for magnetic resonance imaging and photodynamic therapy G Li, A Slansky, MP Dobhal, LN Goswami, A Graham, Y Chen, P Kanter, ... Bioconjugate chemistry 16 (1), 32-42, 2005 | 89 | 2005 |
Light delivery over extended time periods enhances the effectiveness of photodynamic therapy M Seshadri, DA Bellnier, LA Vaughan, JA Spernyak, R Mazurchuk, ... Clinical Cancer Research 14 (9), 2796-2805, 2008 | 84 | 2008 |
Tumor vascular response to photodynamic therapy and the antivascular agent 5, 6-dimethylxanthenone-4-acetic acid: implications for combination therapy M Seshadri, JA Spernyak, R Mazurchuk, SH Camacho, AR Oseroff, ... Clinical cancer research 11 (11), 4241-4250, 2005 | 77 | 2005 |
A Class of FeIII Macrocyclic Complexes with Alcohol Donor Groups as Effective T1 MRI Contrast Agents EM Snyder, D Asik, SM Abozeid, A Burgio, G Bateman, SG Turowski, ... Angewandte Chemie 132 (6), 2435-2440, 2020 | 76 | 2020 |
Metabolic imaging of rat brain during pharmacologically-induced tinnitus AK Paul, E Lobarinas, R Simmons, D Wack, JC Luisi, J Spernyak, ... Neuroimage 44 (2), 312-318, 2009 | 76 | 2009 |
High correlation of whole-body red fluorescent protein imaging and magnetic resonance imaging on an orthotopic model of pancreatic cancer M Bouvet, J Spernyak, MH Katz, RV Mazurchuk, S Takimoto, R Bernacki, ... Cancer research 65 (21), 9829-9833, 2005 | 71 | 2005 |
Fast stereolithography printing of large‐scale biocompatible hydrogel models N Anandakrishnan, H Ye, Z Guo, Z Chen, KI Mentkowski, JK Lang, ... Advanced healthcare materials 10 (10), 2002103, 2021 | 66 | 2021 |
Lack of microvessels in well-differentiated regions of human head and neck squamous cell carcinoma A253 associated with functional magnetic resonance imaging detectable hypoxia … A Bhattacharya, K Tóth, R Mazurchuk, JA Spernyak, HK Slocum, ... Clinical cancer research 10 (23), 8005-8017, 2004 | 63 | 2004 |
Multifunctional Liposomes for Image‐Guided Intratumoral Chemo‐Phototherapy D Miranda, K Carter, D Luo, S Shao, J Geng, C Li, U Chitgupi, ... Advanced healthcare materials 6 (16), 1700253, 2017 | 56 | 2017 |
Gear up for a pH shift: A responsive iron (II) 2-amino-6-picolyl-appended macrocyclic paracest agent that protonates at a pendent group PB Tsitovich, JM Cox, JA Spernyak, JR Morrow Inorganic chemistry 55 (22), 12001-12010, 2016 | 56 | 2016 |
Visualizing the acute effects of vascular-targeted therapy in vivo using intravital microscopy and magnetic resonance imaging: correlation with endothelial apoptosis, cytokine … M Seshadri, JA Spernyak, PG Maier, RT Cheney, R Mazurchuk, ... Neoplasia 9 (2), 128-135, 2007 | 54 | 2007 |
Seven-Coordinate CoII, FeII and Six-Coordinate NiII Amide-Appended Macrocyclic Complexes as ParaCEST Agents in Biological Media AO Olatunde, JM Cox, MD Daddario, JA Spernyak, JB Benedict, ... Inorganic Chemistry 53 (16), 8311-8321, 2014 | 53 | 2014 |
Hexylether derivative of pyropheophorbide-a (HPPH) on conjugating with 3gadolinium (III) aminobenzyldiethylenetriaminepentaacetic acid shows potential for in vivo tumor imaging … JA Spernyak, WH White III, M Ethirajan, NJ Patel, L Goswami, Y Chen, ... Bioconjugate chemistry 21 (5), 828-835, 2010 | 53 | 2010 |