| Effects of glycosylation on the stability of protein pharmaceuticals RJ Solá, KAI Griebenow Journal of pharmaceutical sciences 98 (4), 1223-1245, 2009 | 686 | 2009 |
| On protein denaturation in aqueous− organic mixtures but not in pure organic solvents K Griebenow, AM Klibanov Journal of the American Chemical Society 118 (47), 11695-11700, 1996 | 534 | 1996 |
| Glycosylation of therapeutic proteins: an effective strategy to optimize efficacy RJ Solá, K Griebenow BioDrugs 24 (1), 9-21, 2010 | 507 | 2010 |
| Lyophilization-induced reversible changes in the secondary structure of proteins. K Griebenow, AM Klibanov Proceedings of the National Academy of Sciences 92 (24), 10969-10976, 1995 | 492 | 1995 |
| Protein spray-freeze drying. Effect of atomization conditions on particle size and stability HR Costantino, L Firouzabadian, K Hogeland, C Wu, C Beganski, ... Pharmaceutical research 17, 1374-1382, 2000 | 270 | 2000 |
| FTIR characterization of the secondary structure of proteins encapsulated within PLGA microspheres K Fu, K Griebenow, L Hsieh, AM Klibanov, R Langera Journal of Controlled Release 58 (3), 357-366, 1999 | 250 | 1999 |
| Non-aqueous encapsulation of excipient-stabilized spray-freeze dried BSA into poly (lactide-co-glycolide) microspheres results in release of native protein KG Carrasquillo, AM Stanley, JC Aponte-Carro, P De Jésus, ... Journal of Controlled Release 76 (3), 199-208, 2001 | 243 | 2001 |
| Recent trends in stabilizing protein structure upon encapsulation and release from bioerodible polymers C Pérez, IJ Castellanos, HR Costantino, W Al‐Azzam, K Griebenow Journal of Pharmacy and Pharmacology 54 (3), 301-313, 2002 | 230 | 2002 |
| Effect of excipients on the stability and structure of lyophilized recombinant human growth hormone HR Costantino, KG Carrasquillo, RA Cordero, M Mumenthaler, CC Hsu, ... Journal of pharmaceutical sciences 87 (11), 1412-1420, 1998 | 215 | 1998 |
| Protein spray freeze drying. 2. Effect of formulation variables on particle size and stability HR Costantino, L Firouzabadian, C Wu, KG Carrasquillo, K Griebenow, ... Journal of pharmaceutical sciences 91 (2), 388-395, 2002 | 179 | 2002 |
| Stable conformations of tripeptides in aqueous solution studied by UV circular dichroism spectroscopy F Eker, K Griebenow, R Schweitzer-Stenner Journal of the American Chemical Society 125 (27), 8178-8185, 2003 | 171 | 2003 |
| Can conformational changes be responsible for solvent and excipient effects on the catalytic behavior of subtilisin Carlsberg in organic solvents? K Griebenow, AM Klibanov Biotechnology and Bioengineering 53 (4), 351-362, 1997 | 166 | 1997 |
| Fourier-transform infrared spectroscopic investigation of protein stability in the lyophilized form HR Costantino, K Griebenow, P Mishra, R Langer, AM Klibanov Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular …, 1995 | 162 | 1995 |
| Poly (ethylene glycol) as stabilizer and emulsifying agent: a novel stabilization approach preventing aggregation and inactivation of proteins upon encapsulation in bioerodible … IJ Castellanos, R Crespo, K Griebenow Journal of controlled release 88 (1), 135-145, 2003 | 160 | 2003 |
| Dihedral angles of trialanine in D2O determined by combining FTIR and polarized visible Raman spectroscopy R Schweitzer-Stenner, F Eker, Q Huang, K Griebenow Journal of the American Chemical Society 123 (39), 9628-9633, 2001 | 153 | 2001 |
| The conformation of tetraalanine in water determined by polarized Raman, FT-IR, and VCD spectroscopy R Schweitzer-Stenner, F Eker, K Griebenow, X Cao, LA Nafie Journal of the American Chemical Society 126 (9), 2768-2776, 2004 | 152 | 2004 |
| Modulation of protein biophysical properties by chemical glycosylation: biochemical insights and biomedical implications RJ Solá, JA Rodríguez-Martínez, K Griebenow Cellular and Molecular Life Sciences 64 (16), 2133-2152, 2007 | 147 | 2007 |
| Preferred peptide backbone conformations in the unfolded state revealed by the structure analysis of alanine-based (AXA) tripeptides in aqueous solution F Eker, K Griebenow, X Cao, LA Nafie, R Schweitzer-Stenner Proceedings of the National Academy of Sciences 101 (27), 10054-10059, 2004 | 143 | 2004 |
| Stabilization of α‐chymotrypsin upon PEGylation correlates with reduced structural dynamics JA Rodríguez‐Martínez, RJ Solá, B Castillo, HR Cintrón‐Colón, ... Biotechnology and bioengineering 101 (6), 1142-1149, 2008 | 132 | 2008 |
| Improved enzyme activity and enantioselectivity in organic solvents by methyl-β-cyclodextrin K Griebenow, YD Laureano, AM Santos, IM Clemente, L Rodríguez, ... Journal of the American Chemical Society 121 (36), 8157-8163, 1999 | 132 | 1999 |
Alfred HolzwarthProf. of Biophysics, Max-Planck-Institute (ret.)Verified email at cec.mpg.de
