Kai Griebenow
Cited by
Cited by
Effects of glycosylation on the stability of protein pharmaceuticals
RJ Solá, KAI Griebenow
Journal of pharmaceutical sciences 98 (4), 1223-1245, 2009
On protein denaturation in aqueous− organic mixtures but not in pure organic solvents
K Griebenow, AM Klibanov
Journal of the American Chemical Society 118 (47), 11695-11700, 1996
Glycosylation of therapeutic proteins: an effective strategy to optimize efficacy
RJ Solá, K Griebenow
BioDrugs 24 (1), 9-21, 2010
Lyophilization-induced reversible changes in the secondary structure of proteins.
K Griebenow, AM Klibanov
Proceedings of the National Academy of Sciences 92 (24), 10969-10976, 1995
Protein spray-freeze drying. Effect of atomization conditions on particle size and stability
HR Costantino, L Firouzabadian, K Hogeland, C Wu, C Beganski, ...
Pharmaceutical research 17, 1374-1382, 2000
FTIR characterization of the secondary structure of proteins encapsulated within PLGA microspheres
K Fu, K Griebenow, L Hsieh, AM Klibanov, R Langera
Journal of Controlled Release 58 (3), 357-366, 1999
Non-aqueous encapsulation of excipient-stabilized spray-freeze dried BSA into poly (lactide-co-glycolide) microspheres results in release of native protein
KG Carrasquillo, AM Stanley, JC Aponte-Carro, P De Jésus, ...
Journal of Controlled Release 76 (3), 199-208, 2001
Recent trends in stabilizing protein structure upon encapsulation and release from bioerodible polymers
C Pérez, IJ Castellanos, HR Costantino, W Al‐Azzam, K Griebenow
Journal of Pharmacy and Pharmacology 54 (3), 301-313, 2002
Effect of excipients on the stability and structure of lyophilized recombinant human growth hormone
HR Costantino, KG Carrasquillo, RA Cordero, M Mumenthaler, CC Hsu, ...
Journal of pharmaceutical sciences 87 (11), 1412-1420, 1998
Protein spray freeze drying. 2. Effect of formulation variables on particle size and stability
HR Costantino, L Firouzabadian, C Wu, KG Carrasquillo, K Griebenow, ...
Journal of pharmaceutical sciences 91 (2), 388-395, 2002
Stable conformations of tripeptides in aqueous solution studied by UV circular dichroism spectroscopy
F Eker, K Griebenow, R Schweitzer-Stenner
Journal of the American Chemical Society 125 (27), 8178-8185, 2003
Poly (ethylene glycol) as stabilizer and emulsifying agent: a novel stabilization approach preventing aggregation and inactivation of proteins upon encapsulation in bioerodible …
IJ Castellanos, R Crespo, K Griebenow
Journal of controlled release 88 (1), 135-145, 2003
Can conformational changes be responsible for solvent and excipient effects on the catalytic behavior of subtilisin Carlsberg in organic solvents?
K Griebenow, AM Klibanov
Biotechnology and Bioengineering 53 (4), 351-362, 1997
Fourier-transform infrared spectroscopic investigation of protein stability in the lyophilized form
HR Costantino, K Griebenow, P Mishra, R Langer, AM Klibanov
Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular …, 1995
The conformation of tetraalanine in water determined by polarized Raman, FT-IR, and VCD spectroscopy
R Schweitzer-Stenner, F Eker, K Griebenow, X Cao, LA Nafie
Journal of the American Chemical Society 126 (9), 2768-2776, 2004
Dihedral angles of trialanine in D2O determined by combining FTIR and polarized visible Raman spectroscopy
R Schweitzer-Stenner, F Eker, Q Huang, K Griebenow
Journal of the American Chemical Society 123 (39), 9628-9633, 2001
Modulation of protein biophysical properties by chemical glycosylation: biochemical insights and biomedical implications
RJ Solá, JA Rodríguez-Martínez, K Griebenow
Cellular and Molecular Life Sciences 64 (16), 2133-2152, 2007
Preferred peptide backbone conformations in the unfolded state revealed by the structure analysis of alanine-based (AXA) tripeptides in aqueous solution
F Eker, K Griebenow, X Cao, LA Nafie, R Schweitzer-Stenner
Proceedings of the National Academy of Sciences 101 (27), 10054-10059, 2004
Stabilization of α‐chymotrypsin upon PEGylation correlates with reduced structural dynamics
JA Rodríguez‐Martínez, RJ Solá, B Castillo, HR Cintrón‐Colón, ...
Biotechnology and bioengineering 101 (6), 1142-1149, 2008
Improved enzyme activity and enantioselectivity in organic solvents by methyl-β-cyclodextrin
K Griebenow, YD Laureano, AM Santos, IM Clemente, L Rodríguez, ...
Journal of the American Chemical Society 121 (36), 8157-8163, 1999
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