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Niloufar Salehi
Niloufar Salehi
Ph.D. ChE & PharmSci, University of Michigan
Bestätigte E-Mail-Adresse bei umich.edu
Titel
Zitiert von
Zitiert von
Jahr
Low Buffer Capacity and Alternating Motility along the Human Gastrointestinal Tract: Implications for in Vivo Dissolution and Absorption of Ionizable Drugs
B Hens, Y Tsume, M Bermejo, P Paixao, MJ Koenigsknecht, JR Baker, ...
Molecular pharmaceutics 14 (12), 4281-4294, 2017
1192017
Formulation predictive dissolution (fPD) testing to advance oral drug product development: An introduction to the US FDA funded ‘21st Century BA/BE’project
B Hens, PD Sinko, N Job, M Dean, J Al-Gousous, N Salehi, RM Ziff, ...
International journal of pharmaceutics 548 (1), 120-127, 2018
502018
Mass Transport Analysis of Bicarbonate Buffer: Effect of the CO2–H2CO3 Hydration–Dehydration Kinetics in the Fluid Boundary Layer and the Apparent Effective p K a Controlling …
J Al-Gousous, N Salehi, GE Amidon, RM Ziff, P Langguth, GL Amidon
Molecular Pharmaceutics 16 (6), 2626-2635, 2019
462019
Mechanistic analysis and experimental verification of bicarbonate-controlled enteric coat dissolution: Potential in vivo implications
J Al-Gousous, H Ruan, JA Blechar, KX Sun, N Salehi, P Langguth, ...
European Journal of Pharmaceutics and Biopharmaceutics 139, 47-58, 2019
352019
Hierarchical mass transfer analysis of drug particle dissolution, highlighting the hydrodynamics, pH, particle size, and buffer effects for the dissolution of ionizable and …
N Salehi, J Al-Gousous, DM Mudie, GL Amidon, RM Ziff, GE Amidon
Molecular Pharmaceutics 17 (10), 3870-3884, 2020
332020
Mass Transport Analysis of the Enhanced Buffer Capacity of the Bicarbonate–CO2 Buffer in a Phase-Heterogenous System: Physiological and Pharmaceutical …
J Al-Gousous, KX Sun, DP McNamara, B Hens, N Salehi, P Langguth, ...
Molecular pharmaceutics 15 (11), 5291-5301, 2018
322018
Gastric emptying and intestinal appearance of nonabsorbable drugs phenol red and paromomycin in human subjects: A multi-compartment stomach approach
P Paixão, M Bermejo, B Hens, Y Tsume, J Dickens, K Shedden, N Salehi, ...
European Journal of Pharmaceutics and Biopharmaceutics 129, 162-174, 2018
312018
Linking the gastrointestinal behavior of ibuprofen with the systemic exposure between and within humans—part 1: fasted state conditions
M Bermejo, P Paixão, B Hens, Y Tsume, MJ Koenigsknecht, JR Baker, ...
Molecular pharmaceutics 15 (12), 5454-5467, 2018
272018
Improving dissolution behavior and oral absorption of drugs with pH-dependent solubility using ph modifiers: a physiologically realistic mass transport analysis
N Salehi, G Kuminek, J Al-Gousous, DC Sperry, DE Greenwood, ...
Molecular Pharmaceutics 18 (9), 3326-3341, 2021
202021
Linking the gastrointestinal behavior of ibuprofen with the systemic exposure between and within humans—part 2: fed state
P Paixão, M Bermejo, B Hens, Y Tsume, J Dickens, K Shedden, N Salehi, ...
Molecular pharmaceutics 15 (12), 5468-5478, 2018
142018
Ultrathin, large-area membrane diffusion cell for ph-dependent simultaneous dissolution and absorption studies
PD Sinko, S Harris, N Salehi, PJ Meyer, GL Amidon, GE Amidon
Molecular Pharmaceutics 17 (7), 2319-2328, 2020
112020
Evaluating the IVIVC by combining tiny-TIM outputs and compartmental PK model to predict oral exposure for different formulations of ibuprofen
PC Chiang, J Liu, K Nagapudi, R Wu, MJ Dolton, N Salehi, G Amidon
Journal of Pharmaceutical Sciences 111 (7), 2018-2029, 2022
102022
Use of gastrointestinal simulator, mass transport analysis, and absorption simulation to investigate the impact of ph modifiers in mitigating weakly basic drugs’ performance …
G Kuminek, N Salehi, NM Waltz, DC Sperry, DE Greenwood, SS Hate, ...
Molecular Pharmaceutics 20 (1), 147-158, 2022
42022
Mechanistic Mass Transport Modeling of Ionizable Drug Dissolution Under In Vivo-Relevant Buffer and Hydrodynamical Conditions
N Salehi, J Al-Gousous, G Amidon, G Amidon, RM Ziff
2019 AIChE Annual Meeting, 2019
22019
Particle Size, Dose, and Confinement Affect Passive Diffusion Flux through the Membrane Concentration Boundary Layer
PD Sinko, N Salehi, T Halseth, PJ Meyer, GL Amidon, RM Ziff, GE Amidon
Molecular Pharmaceutics 21 (1), 201-215, 2023
12023
Summary of the In Vivo Predictive Dissolution (iPD): Oral Drug Delivery (ODD) Conference 2018
B Hens, J Al-Gousous, K Wang, N Salehi, RM Ziff, Y Tsume, M Bermejo, ...
Dissolution Technologies 25 (2), 2018
12018
Solubility vs Dissolution in Physiological Bicarbonate Buffer
F Claussen, J Al-Gousous, N Salehi, MA Garcia, GL Amidon, P Langguth
Pharmaceutical Research, 1-9, 2024
2024
Comparative Evaluation of Dissolution Performance in a USP 2 Setup and Alternative Stirrers and Vessel Designs: A Systematic Computational Investigation
N Salehi, J Al-Gousous, B Hens, GL Amidon, RM Ziff, GE Amidon
Molecular Pharmaceutics 21 (5), 2406-2414, 2024
2024
Voices in Molecular Pharmaceutics: Meet Dr. Niloufar Salehi, an Enthusiastic Developer of Physiologically Based Biopharmaceutical Models
N Salehi
Molecular Pharmaceutics 20 (9), 4342-4343, 2023
2023
Drug Delivery Technology Evaluating the IVIVC by Combining Tiny-tim Outputs and Compartmental PK Model to Predict Oral Exposure for Different Formulations of Ibuprofen
PC Chiang, J Liu, K Nagapudi, R Wu, MJ Dolton, N Salehi, G Amidon
JOURNAL OF PHARMACEUTICAL SCIENCES 111 (7), 2018-2029, 2022
2022
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