Effects of glycosylation on the stability of protein pharmaceuticals RJ Solá, KAI Griebenow Journal of pharmaceutical sciences 98 (4), 1223-1245, 2009 | 725 | 2009 |
Glycosylation of therapeutic proteins: an effective strategy to optimize efficacy RJ Solá, K Griebenow BioDrugs 24 (1), 9-21, 2010 | 536 | 2010 |
Halogen bond tunability I: the effects of aromatic fluorine substitution on the strengths of halogen-bonding interactions involving chlorine, bromine, and iodine KE Riley, JS Murray, J Fanfrlík, J Řezáč, RJ Solá, MC Concha, FM Ramos, ... Journal of molecular modeling 17, 3309-3318, 2011 | 413 | 2011 |
Halogen bond tunability II: the varying roles of electrostatic and dispersion contributions to attraction in halogen bonds KE Riley, JS Murray, J Fanfrlík, J Řezáč, RJ Solá, MC Concha, FM Ramos, ... Journal of molecular modeling 19, 4651-4659, 2013 | 205 | 2013 |
Modulation of protein biophysical properties by chemical glycosylation: biochemical insights and biomedical implications RJ Solá, JA Rodríguez-Martínez, K Griebenow Cellular and Molecular Life Sciences 64 (16), 2133-2152, 2007 | 148 | 2007 |
Stabilization of α‐chymotrypsin upon PEGylation correlates with reduced structural dynamics JA Rodríguez‐Martínez, RJ Solá, B Castillo, HR Cintrón‐Colón, ... Biotechnology and bioengineering 101 (6), 1142-1149, 2008 | 140 | 2008 |
Enzymatic activity and thermal stability of PEG-α-chymotrypsin conjugates JA Rodríguez-Martínez, I Rivera-Rivera, RJ Solá, K Griebenow Biotechnology letters 31, 883-887, 2009 | 84 | 2009 |
Proteomic analysis of plasma from patients with systemic lupus erythematosus: Increased presence of haptoglobin α2 polypeptide chains over the α1 isoforms EJ Pavón, P Muñoz, A Lario, V Longobardo, M Carrascal, J Abián, ... Proteomics 6 (S1), S282-S292, 2006 | 72 | 2006 |
Engineering of protein thermodynamic, kinetic, and colloidal stability: Chemical glycosylation with monofunctionally activated glycans RJ Solá, W Al‐Azzam, K Griebenow Biotechnology and bioengineering 94 (6), 1072-1079, 2006 | 67 | 2006 |
Chemical glycosylation: New insights on the interrelation between protein structural mobility, thermodynamic stability, and catalysis RJ Solá, K Griebenow FEBS letters 580 (6), 1685-1690, 2006 | 64 | 2006 |
Effect of PEG modification on subtilisin Carlsberg activity, enantioselectivity, and structural dynamics in 1, 4‐dioxane B Castillo, RJ Solá, A Ferrer, G Barletta, K Griebenow Biotechnology and bioengineering 99 (1), 9-17, 2008 | 51 | 2008 |
Influence of modulated structural dynamics on the kinetics of α‐chymotrypsin catalysis: Insights through chemical glycosylation, molecular dynamics and domain motion analysis RJ Sola, K Griebenow The FEBS journal 273 (23), 5303-5319, 2006 | 51 | 2006 |
The relation between moisture-induced aggregation and structural changes in lyophilized insulin GM Flores-Fernández, RJ Solá, K Griebenow Journal of Pharmacy and Pharmacology 61 (11), 1555-1561, 2009 | 36 | 2009 |
Moisture-induced solid state instabilities in α-chymotrypsin and their reduction through chemical glycosylation GM Flores-Fernández, M Pagán, M Almenas, RJ Solá, K Griebenow BMC biotechnology 10, 1-11, 2010 | 28 | 2010 |
On the role of protein structural dynamics in the catalytic activity and thermostability of serine protease subtilisin Carlsberg M Pagán, RJ Solá, K Griebenow Biotechnology and bioengineering 103 (1), 77-84, 2009 | 21 | 2009 |
Increasing alpha-chymotrypsin thermodynamic stability upon PEGylation correlates with reduced structural dynamics JA Rodriguez-Martinez, RJ Sola, B Castillo, I Rivera-Rivera, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 237, 412-412, 2009 | | 2009 |
B3 On the role of protein structural dynamics in the catalytic activity and thermostability of serine protease subtilisin Carlsberg RJ Sola, K Griebenow GLYCOCONJUGATE JOURNAL 26 (7), 119-119, 2009 | | 2009 |