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Ricardo J Sola Rosario
Ricardo J Sola Rosario
Amgen - Principal Scientist - Attribute Sciences Team Leader
Verified email at amgen.com
Title
Cited by
Cited by
Year
Effects of glycosylation on the stability of protein pharmaceuticals
RJ Solá, KAI Griebenow
Journal of pharmaceutical sciences 98 (4), 1223-1245, 2009
7252009
Glycosylation of therapeutic proteins: an effective strategy to optimize efficacy
RJ Solá, K Griebenow
BioDrugs 24 (1), 9-21, 2010
5362010
Halogen bond tunability I: the effects of aromatic fluorine substitution on the strengths of halogen-bonding interactions involving chlorine, bromine, and iodine
KE Riley, JS Murray, J Fanfrlík, J Řezáč, RJ Solá, MC Concha, FM Ramos, ...
Journal of molecular modeling 17, 3309-3318, 2011
4132011
Halogen bond tunability II: the varying roles of electrostatic and dispersion contributions to attraction in halogen bonds
KE Riley, JS Murray, J Fanfrlík, J Řezáč, RJ Solá, MC Concha, FM Ramos, ...
Journal of molecular modeling 19, 4651-4659, 2013
2052013
Modulation of protein biophysical properties by chemical glycosylation: biochemical insights and biomedical implications
RJ Solá, JA Rodríguez-Martínez, K Griebenow
Cellular and Molecular Life Sciences 64 (16), 2133-2152, 2007
1482007
Stabilization of α‐chymotrypsin upon PEGylation correlates with reduced structural dynamics
JA Rodríguez‐Martínez, RJ Solá, B Castillo, HR Cintrón‐Colón, ...
Biotechnology and bioengineering 101 (6), 1142-1149, 2008
1402008
Enzymatic activity and thermal stability of PEG-α-chymotrypsin conjugates
JA Rodríguez-Martínez, I Rivera-Rivera, RJ Solá, K Griebenow
Biotechnology letters 31, 883-887, 2009
842009
Proteomic analysis of plasma from patients with systemic lupus erythematosus: Increased presence of haptoglobin α2 polypeptide chains over the α1 isoforms
EJ Pavón, P Muñoz, A Lario, V Longobardo, M Carrascal, J Abián, ...
Proteomics 6 (S1), S282-S292, 2006
722006
Engineering of protein thermodynamic, kinetic, and colloidal stability: Chemical glycosylation with monofunctionally activated glycans
RJ Solá, W Al‐Azzam, K Griebenow
Biotechnology and bioengineering 94 (6), 1072-1079, 2006
672006
Chemical glycosylation: New insights on the interrelation between protein structural mobility, thermodynamic stability, and catalysis
RJ Solá, K Griebenow
FEBS letters 580 (6), 1685-1690, 2006
642006
Effect of PEG modification on subtilisin Carlsberg activity, enantioselectivity, and structural dynamics in 1, 4‐dioxane
B Castillo, RJ Solá, A Ferrer, G Barletta, K Griebenow
Biotechnology and bioengineering 99 (1), 9-17, 2008
512008
Influence of modulated structural dynamics on the kinetics of α‐chymotrypsin catalysis: Insights through chemical glycosylation, molecular dynamics and domain motion analysis
RJ Sola, K Griebenow
The FEBS journal 273 (23), 5303-5319, 2006
512006
The relation between moisture-induced aggregation and structural changes in lyophilized insulin
GM Flores-Fernández, RJ Solá, K Griebenow
Journal of Pharmacy and Pharmacology 61 (11), 1555-1561, 2009
362009
Moisture-induced solid state instabilities in α-chymotrypsin and their reduction through chemical glycosylation
GM Flores-Fernández, M Pagán, M Almenas, RJ Solá, K Griebenow
BMC biotechnology 10, 1-11, 2010
282010
On the role of protein structural dynamics in the catalytic activity and thermostability of serine protease subtilisin Carlsberg
M Pagán, RJ Solá, K Griebenow
Biotechnology and bioengineering 103 (1), 77-84, 2009
212009
Increasing alpha-chymotrypsin thermodynamic stability upon PEGylation correlates with reduced structural dynamics
JA Rodriguez-Martinez, RJ Sola, B Castillo, I Rivera-Rivera, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 237, 412-412, 2009
2009
B3 On the role of protein structural dynamics in the catalytic activity and thermostability of serine protease subtilisin Carlsberg
RJ Sola, K Griebenow
GLYCOCONJUGATE JOURNAL 26 (7), 119-119, 2009
2009
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