Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape PA Koenig, H Das, H Liu, BM Kümmerer, FN Gohr, LM Jenster, ... Science 371 (6530), eabe6230, 2021 | 328 | 2021 |
SARS-CoV-2 exposure, symptoms and seroprevalence in healthcare workers in Sweden AS Rudberg, S Havervall, A Månberg, A Jernbom Falk, K Aguilera, H Ng, ... Nature communications 11 (1), 5064, 2020 | 322 | 2020 |
An alpaca nanobody neutralizes SARS-CoV-2 by blocking receptor interaction L Hanke, L Vidakovics Perez, DJ Sheward, H Das, T Schulte, ... Nature communications 11 (1), 4420, 2020 | 288 | 2020 |
Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2 TF Custódio, H Das, DJ Sheward, L Hanke, S Pazicky, J Pieprzyk, ... Nature communications 11 (1), 5588, 2020 | 149 | 2020 |
Intracellular expression of camelid single-domain antibodies specific for influenza virus nucleoprotein uncovers distinct features of its nuclear localization J Ashour, FI Schmidt, L Hanke, J Cragnolini, M Cavallari, A Altenburg, ... Journal of virology 89 (5), 2792-2800, 2015 | 66 | 2015 |
Generation of immunity against pathogens via single-domain antibody–antigen constructs JN Duarte, JJ Cragnolini, LK Swee, AM Bilate, J Bader, JR Ingram, ... The Journal of Immunology 197 (12), 4838-4847, 2016 | 63 | 2016 |
SARS-CoV-2 protein subunit vaccination of mice and rhesus macaques elicits potent and durable neutralizing antibody responses M Mandolesi, DJ Sheward, L Hanke, J Ma, P Pushparaj, LP Vidakovics, ... Cell Reports Medicine 2 (4), 2021 | 55 | 2021 |
A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo L Hanke, H Das, DJ Sheward, L Perez Vidakovics, E Urgard, ... Nature communications 13 (1), 155, 2022 | 54 | 2022 |
Phenotypic lentivirus screens to identify functional single domain antibodies FI Schmidt, L Hanke, B Morin, R Brewer, V Brusic, SPJ Whelan, ... Nature microbiology 1 (8), 1-10, 2016 | 51 | 2016 |
Multianalyte serology in home-sampled blood enables an unbiased assessment of the immune response against SARS-CoV-2 N Roxhed, A Bendes, M Dale, C Mattsson, L Hanke, T Dodig-Crnković, ... Nature Communications 12 (1), 3695, 2021 | 46* | 2021 |
Seropositivity in blood donors and pregnant women during the first year of SARS‐CoV‐2 transmission in Stockholm, Sweden X Castro Dopico, S Muschiol, M Christian, L Hanke, DJ Sheward, ... Journal of Internal Medicine, 2021 | 46* | 2021 |
Unrestrained AMPylation targets cytosolic chaperones and activates the heat shock response MC Truttmann, X Zheng, L Hanke, JR Damon, M Grootveld, J Krakowiak, ... Proceedings of the National Academy of Sciences 114 (2), E152-E160, 2017 | 38 | 2017 |
Adjuvanted SARS-CoV-2 spike protein elicits neutralizing antibodies and CD4 T cell responses after a single immunization in mice K Wørzner, DJ Sheward, ST Schmidt, L Hanke, J Zimmermann, ... EBioMedicine 63, 2021 | 33 | 2021 |
Systematic evaluation of SARS‐CoV‐2 antigens enables a highly specific and sensitive multiplex serological COVID‐19 assay S Hober, C Hellström, J Olofsson, E Andersson, S Bergström, ... Clinical & Translational Immunology 10 (7), e1312, 2021 | 29 | 2021 |
Structural basis of Omicron neutralization by affinity-matured public antibodies DJ Sheward, P Pushparaj, H Das, C Kim, S Kim, L Hanke, R Dyrdak, ... bioRxiv, 2022.01. 03.474825, 2022 | 28 | 2022 |
Picomolar SARS-CoV-2 neutralization using multi-arm PEG nanobody constructs A Moliner-Morro, D J. Sheward, V Karl, L Perez Vidakovics, B Murrell, ... Biomolecules 10 (12), 1661, 2020 | 28 | 2020 |
The antiviral mechanism of an influenza A virus nucleoprotein-specific single-domain antibody fragment L Hanke, KE Knockenhauer, RC Brewer, E van Diest, FI Schmidt, ... MBio 7 (6), 10.1128/mbio. 01569-16, 2016 | 28 | 2016 |
DNA-launched RNA replicon vaccines induce potent anti-SARS-CoV-2 immune responses in mice I Szurgot, L Hanke, DJ Sheward, LP Vidakovics, B Murrell, GM McInerney, ... Scientific Reports 11 (1), 3125, 2021 | 24 | 2021 |
Beta RBD boost broadens antibody-mediated protection against SARS-CoV-2 variants in animal models DJ Sheward, M Mandolesi, E Urgard, C Kim, L Hanke, LP Vidakovics, ... Cell Reports Medicine 2 (11), 100450, 2021 | 22 | 2021 |
Vesicular stomatitis virus N protein‐specific single‐domain antibody fragments inhibit replication L Hanke, FI Schmidt, KE Knockenhauer, B Morin, SPJ Whelan, ... EMBO reports 18 (6), 1027-1037, 2017 | 22 | 2017 |