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Morkos Henen
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Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansion
IW Tengesdal, DR Menon, DG Osborne, CP Neff, NE Powers, F Gamboni, ...
Proceedings of the National Academy of Sciences 118 (10), e2000915118, 2021
1292021
Cooperative unfolding of compact conformations of the intrinsically disordered protein osteopontin
D Kurzbach, G Platzer, TC Schwarz, MA Henen, R Konrat, ...
Biochemistry 52 (31), 5167-5175, 2013
1192013
Stabilizer‐Guided Inhibition of Protein–Protein Interactions
LG Milroy, M Bartel, MA Henen, S Leysen, JMC Adriaans, L Brunsveld, ...
Angewandte Chemie International Edition 54 (52), 15720-15724, 2015
742015
Structural biology of betaglycan and endoglin, membrane-bound co-receptors of the TGF-beta family
SK Kim, MA Henen, AP Hinck
Experimental Biology and Medicine 244 (17), 1547-1558, 2019
612019
[1,2,4]Triazolo[4,3-a]quinoxaline: synthesis, antiviral, and antimicrobial activities
MA Henen, SAA El Bialy, FE Goda, MNA Nasr, HM Eisa
Medicinal Chemistry Research 21, 2368-2378, 2012
612012
Binding properties of the transforming growth factor-β coreceptor betaglycan: proposed mechanism for potentiation of receptor complex assembly and signaling
MM Villarreal, SK Kim, L Barron, R Kodali, J Baardsnes, CS Hinck, ...
Biochemistry 55 (49), 6880-6896, 2016
502016
A transient helix in the disordered region of dynein light intermediate chain links the motor to structurally diverse adaptors for cargo transport
MA Henen
Plos Biology, 2019
482019
Microbiota-derived butyrate is an endogenous HIF prolyl hydroxylase inhibitor
RX Wang, MA Henen, JS Lee, B Vögeli, SP Colgan
Gut Microbes 13 (1), 1938380, 2021
472021
Recognition of non-CpG repeats in Alu and ribosomal RNAs by the Z-RNA binding domain of ADAR1 induces AZ junctions
PJ Nichols, S Bevers, M Henen, JS Kieft, Q Vicens, B Vögeli
Nature Communications 12 (1), 793, 2021
462021
High-resolution small RNA structures from exact nuclear Overhauser enhancement measurements without additional restraints
PJ Nichols, MA Henen, A Born, D Strotz, P Güntert, B Vögeli
Communications biology 1 (1), 61, 2018
372018
Protonation‐dependent conformational variability of intrinsically disordered proteins
L Geist, MA Henen, S Haiderer, TC Schwarz, D Kurzbach, ...
Protein Science 22 (9), 1196-1205, 2013
372013
The inherent dynamics and interaction sites of the SARS-CoV-2 nucleocapsid N-terminal region
JS Redzic, E Lee, A Born, A Issaian, MA Henen, PJ Nichols, A Blue, ...
Journal of Molecular Biology 433 (15), 167108, 2021
362021
The exact nuclear overhauser enhancement: recent advances
PJ Nichols, A Born, MA Henen, D Strotz, J Orts, S Olsson, P Güntert, ...
Molecules 22 (7), 1176, 2017
262017
Synthesis, anticancer and antimicrobial evaluation of new benzofuran based derivatives: PI3K inhibition, quorum sensing and molecular modeling study
OA El-Khouly, MA Henen, AA Magda, MI Shabaan, SM El-Messery
Bioorganic & medicinal chemistry 31, 115976, 2021
242021
Microbial-derived indoles inhibit neutrophil myeloperoxidase to diminish bystander tissue damage
EE Alexeev, AS Dowdell, MA Henen, JM Lanis, JS Lee, IM Cartwright, ...
FASEB journal: official publication of the Federation of American Societies …, 2021
232021
Structure and formation of Z-DNA and Z-RNA
JB Krall, PJ Nichols, MA Henen, Q Vicens, B Vögeli
Molecules 28 (2), 843, 2023
222023
TGF-β2 uses the concave surface of its extended finger region to bind betaglycan’s ZP domain via three residues specific to TGF-β and inhibin-α
MA Henen, P Mahlawat, C Zwieb, RB Kodali, CS Hinck, RD Hanna, ...
Journal of Biological Chemistry 294 (9), 3065-3080, 2019
222019
Reconstruction of coupled intra-and interdomain protein motion from nuclear and electron magnetic resonance
A Born, J Soetbeer, F Breitgoff, MA Henen, N Sgourakis, Y Polyhach, ...
Journal of the American Chemical Society 143 (39), 16055-16067, 2021
212021
Extending the applicability of exact nuclear overhauser enhancements to large proteins and RNA
PJ Nichols, A Born, MA Henen, D Strotz, CN Celestine, P Güntert, ...
ChemBioChem 19 (16), 1695-1701, 2018
212018
Synthesis, state-of-the-art NMR-binding and molecular modeling study of new benzimidazole core derivatives as Pin1 inhibitors: Targeting breast cancer
S Nashaat, MA Henen, SM El-Messery, H Eisa
Bioorganic & medicinal chemistry 28 (11), 115495, 2020
182020
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Articles 1–20