Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansion IW Tengesdal, DR Menon, DG Osborne, CP Neff, NE Powers, F Gamboni, ... Proceedings of the National Academy of Sciences 118 (10), e2000915118, 2021 | 129 | 2021 |
Cooperative unfolding of compact conformations of the intrinsically disordered protein osteopontin D Kurzbach, G Platzer, TC Schwarz, MA Henen, R Konrat, ... Biochemistry 52 (31), 5167-5175, 2013 | 119 | 2013 |
Stabilizer‐Guided Inhibition of Protein–Protein Interactions LG Milroy, M Bartel, MA Henen, S Leysen, JMC Adriaans, L Brunsveld, ... Angewandte Chemie International Edition 54 (52), 15720-15724, 2015 | 74 | 2015 |
Structural biology of betaglycan and endoglin, membrane-bound co-receptors of the TGF-beta family SK Kim, MA Henen, AP Hinck Experimental Biology and Medicine 244 (17), 1547-1558, 2019 | 61 | 2019 |
[1,2,4]Triazolo[4,3-a]quinoxaline: synthesis, antiviral, and antimicrobial activities MA Henen, SAA El Bialy, FE Goda, MNA Nasr, HM Eisa Medicinal Chemistry Research 21, 2368-2378, 2012 | 61 | 2012 |
Binding properties of the transforming growth factor-β coreceptor betaglycan: proposed mechanism for potentiation of receptor complex assembly and signaling MM Villarreal, SK Kim, L Barron, R Kodali, J Baardsnes, CS Hinck, ... Biochemistry 55 (49), 6880-6896, 2016 | 50 | 2016 |
A transient helix in the disordered region of dynein light intermediate chain links the motor to structurally diverse adaptors for cargo transport MA Henen Plos Biology, 2019 | 48 | 2019 |
Microbiota-derived butyrate is an endogenous HIF prolyl hydroxylase inhibitor RX Wang, MA Henen, JS Lee, B Vögeli, SP Colgan Gut Microbes 13 (1), 1938380, 2021 | 47 | 2021 |
Recognition of non-CpG repeats in Alu and ribosomal RNAs by the Z-RNA binding domain of ADAR1 induces AZ junctions PJ Nichols, S Bevers, M Henen, JS Kieft, Q Vicens, B Vögeli Nature Communications 12 (1), 793, 2021 | 46 | 2021 |
High-resolution small RNA structures from exact nuclear Overhauser enhancement measurements without additional restraints PJ Nichols, MA Henen, A Born, D Strotz, P Güntert, B Vögeli Communications biology 1 (1), 61, 2018 | 37 | 2018 |
Protonation‐dependent conformational variability of intrinsically disordered proteins L Geist, MA Henen, S Haiderer, TC Schwarz, D Kurzbach, ... Protein Science 22 (9), 1196-1205, 2013 | 37 | 2013 |
The inherent dynamics and interaction sites of the SARS-CoV-2 nucleocapsid N-terminal region JS Redzic, E Lee, A Born, A Issaian, MA Henen, PJ Nichols, A Blue, ... Journal of Molecular Biology 433 (15), 167108, 2021 | 36 | 2021 |
The exact nuclear overhauser enhancement: recent advances PJ Nichols, A Born, MA Henen, D Strotz, J Orts, S Olsson, P Güntert, ... Molecules 22 (7), 1176, 2017 | 26 | 2017 |
Synthesis, anticancer and antimicrobial evaluation of new benzofuran based derivatives: PI3K inhibition, quorum sensing and molecular modeling study OA El-Khouly, MA Henen, AA Magda, MI Shabaan, SM El-Messery Bioorganic & medicinal chemistry 31, 115976, 2021 | 24 | 2021 |
Microbial-derived indoles inhibit neutrophil myeloperoxidase to diminish bystander tissue damage EE Alexeev, AS Dowdell, MA Henen, JM Lanis, JS Lee, IM Cartwright, ... FASEB journal: official publication of the Federation of American Societies …, 2021 | 23 | 2021 |
Structure and formation of Z-DNA and Z-RNA JB Krall, PJ Nichols, MA Henen, Q Vicens, B Vögeli Molecules 28 (2), 843, 2023 | 22 | 2023 |
TGF-β2 uses the concave surface of its extended finger region to bind betaglycan’s ZP domain via three residues specific to TGF-β and inhibin-α MA Henen, P Mahlawat, C Zwieb, RB Kodali, CS Hinck, RD Hanna, ... Journal of Biological Chemistry 294 (9), 3065-3080, 2019 | 22 | 2019 |
Reconstruction of coupled intra-and interdomain protein motion from nuclear and electron magnetic resonance A Born, J Soetbeer, F Breitgoff, MA Henen, N Sgourakis, Y Polyhach, ... Journal of the American Chemical Society 143 (39), 16055-16067, 2021 | 21 | 2021 |
Extending the applicability of exact nuclear overhauser enhancements to large proteins and RNA PJ Nichols, A Born, MA Henen, D Strotz, CN Celestine, P Güntert, ... ChemBioChem 19 (16), 1695-1701, 2018 | 21 | 2018 |
Synthesis, state-of-the-art NMR-binding and molecular modeling study of new benzimidazole core derivatives as Pin1 inhibitors: Targeting breast cancer S Nashaat, MA Henen, SM El-Messery, H Eisa Bioorganic & medicinal chemistry 28 (11), 115495, 2020 | 18 | 2020 |