Base-base mismatches. Thermodynamics of double helix formation for dCA3XA3G + dCT3YT3G (X, Y = A,C,G,D F Aboul-Ela, D Koh, I Tinoco Jr, FH Martin Nucleic acids research 13 (13), 4811-4824, 1985 | 600 | 1985 |
The structure of the human immunodeficiency virus type-1 TAR RNA reveals principles of RNA recognition by Tat protein F Aboul-ela, J Karn, G Varani Journal of molecular biology 253 (2), 313-332, 1995 | 523 | 1995 |
NMR investigation of RNA structure G Varani, F Aboul-Ela, FHT Allain Progress in Nuclear Magnetic Resonance Spectroscopy 29 (1-2), 51-127, 1996 | 504 | 1996 |
Base pairing involving deoxyinosine: implications for probe design FH Martin, MM Castro, F Aboul-ela, I Tinoco Jr Nucleic acids research 13 (24), 8927-8938, 1985 | 474 | 1985 |
Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading … B François, RJM Russell, JB Murray, F Aboul-ela, B Masquida, Q Vicens, ... Nucleic acids research 33 (17), 5677-5690, 2005 | 427 | 2005 |
An inhibitor of the Tat/TAR RNA interaction that effectively suppresses HIV-1 replication F Hamy, ER Felder, G Heizmann, J Lazdins, F Aboul-Ela, G Varani, J Karn, ... Proceedings of the National Academy of Sciences 94 (8), 3548-3553, 1997 | 371 | 1997 |
Structure of HIV-1 TAR RNA in the absence of ligands reveals a novel conformation of the trinucleotide bulge F Aboul-ela, J Karn, G Varani Nucleic acids research 24 (20), 3974-3981, 1996 | 339 | 1996 |
NMR study of parallel-stranded tetraplex formation by the hexadeoxynucleotide d(TG4T) F Aboul-Ela, AIH Murchie, DMJ Lilley Nature 360 (6401), 280-282, 1992 | 242 | 1992 |
Design and characterization of libraries of molecular fragments for use in NMR screening against protein targets N Baurin, F Aboul-Ela, X Barril, B Davis, M Drysdale, B Dymock, H Finch, ... Journal of chemical information and computer sciences 44 (6), 2157-2166, 2004 | 185 | 2004 |
Rational design of inhibitors of HIV-1 TAR RNA through the stabilisation of electrostatic “hot spots” B Davis, M Afshar, G Varani, AIH Murchie, J Karn, G Lentzen, M Drysdale, ... Journal of molecular biology 336 (2), 343-356, 2004 | 174 | 2004 |
Structure-based drug design targeting an inactive RNA conformation: exploiting the flexibility of HIV-1 TAR RNA AIH Murchie, B Davis, C Isel, M Afshar, MJ Drysdale, J Bower, AJ Potter, ... Journal of molecular biology 336 (3), 625-638, 2004 | 173 | 2004 |
Solution structure of a parallel-stranded tetraplex formed by d (TG4T) in the presence of sodium ions by nuclear magnetic resonance spectroscopy F Aboul-ela, AIH Murchie, DG Norman, DMJ Lilley Journal of molecular biology 243 (3), 458-471, 1994 | 161 | 1994 |
A conserved RNA structure within the HCV IRES eIF3-binding site AJ Collier, J Gallego, R Klinck, PT Cole, SJ Harris, GP Harrison, ... Nature structural biology 9 (5), 375-380, 2002 | 143 | 2002 |
A potential RNA drug target in the hepatitis C virus internal ribosomal entry site R KLINCK, E WESTHOF, S WALKER, M AFSHAR, A COLLIER, ... Rna 6 (10), 1423-1431, 2000 | 138 | 2000 |
Structural basis for contrasting activities of ribosome binding thiazole antibiotics G Lentzen, R Klinck, N Matassova, F Aboul-ela, AIH Murchie Chemistry & Biology 10 (8), 769-778, 2003 | 131 | 2003 |
Strategies for the design of RNA-binding small molecules F Aboul-ela Future medicinal chemistry 2 (1), 93-119, 2010 | 95 | 2010 |
Towards the discovery of drug-like RNA ligands? N Foloppe, N Matassova, F Aboul-Ela Drug discovery today 11 (21-22), 1019-1027, 2006 | 93 | 2006 |
[5] Two-dimensional gel electrophoresis of circular DNA topoisomers R Bowater, F Aboul-Ela, DMJ Lilley Methods in enzymology 212, 105-120, 1992 | 69 | 1992 |
Helix opening transitions in supercoiled DNA AIH Murchie, R Bowater, F Aboul-ela, DMJ Lilley Biochimica et Biophysica Acta (BBA)-Gene Structure and Expression 1131 (1), 1-15, 1992 | 60 | 1992 |
Linking aptamer‐ligand binding and expression platform folding in riboswitches: prospects for mechanistic modeling and design F Aboul‐ela, W Huang, M Abd Elrahman, V Boyapati, P Li Wiley Interdisciplinary Reviews: RNA 6 (6), 631-650, 2015 | 52 | 2015 |