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Julio Saez Rodriguez
Julio Saez Rodriguez
Heidelberg University
Bestätigte E-Mail-Adresse bei uni-heidelberg.de - Startseite
Titel
Zitiert von
Zitiert von
Jahr
Systematic identification of genomic markers of drug sensitivity in cancer cells
MJ Garnett, EJ Edelman, SJ Heidorn, CD Greenman, A Dastur, KW Lau, ...
Nature 483 (7391), 570-575, 2012
26462012
Prospective derivation of a living organoid biobank of colorectal cancer patients
M Van de Wetering, HE Francies, JM Francis, G Bounova, F Iorio, A Pronk, ...
Cell 161 (4), 933-945, 2015
22542015
A landscape of pharmacogenomic interactions in cancer
F Iorio, TA Knijnenburg, DJ Vis, GR Bignell, MP Menden, M Schubert, ...
Cell 166 (3), 740-754, 2016
18902016
Prioritization of cancer therapeutic targets using CRISPR–Cas9 screens
FM Behan, F Iorio, G Picco, E Gonçalves, CM Beaver, G Migliardi, ...
Nature 568 (7753), 511-516, 2019
11552019
The global phosphorylation landscape of SARS-CoV-2 infection
M Bouhaddou, D Memon, B Meyer, KM White, VV Rezelj, MC Marrero, ...
Cell 182 (3), 685-712. e19, 2020
9462020
A community effort to assess and improve drug sensitivity prediction algorithms
JC Costello, LM Heiser, E Georgii, M Gönen, MP Menden, NJ Wang, ...
Nature biotechnology 32 (12), 1202-1212, 2014
7982014
Benchmark and integration of resources for the estimation of human transcription factor activities
L Garcia-Alonso, CH Holland, MM Ibrahim, D Turei, J Saez-Rodriguez
Genome research 29 (8), 1363-1375, 2019
7862019
A CRISPR dropout screen identifies genetic vulnerabilities and therapeutic targets in acute myeloid leukemia
K Tzelepis, H Koike-Yusa, E De Braekeleer, Y Li, E Metzakopian, ...
Cell reports 17 (4), 1193-1205, 2016
6932016
Critical assessment of automated flow cytometry data analysis techniques
N Aghaeepour, G Finak, FlowCAP Consortium, Dream Consortium, ...
Nature methods 10 (3), 228-238, 2013
6872013
Structural and functional analysis of cellular networks with CellNetAnalyzer
S Klamt, J Saez-Rodriguez, ED Gilles
BMC systems biology 1, 1-13, 2007
6612007
Perturbation-response genes reveal signaling footprints in cancer gene expression
M Schubert, B Klinger, M Klünemann, A Sieber, F Uhlitz, S Sauer, ...
Nature communications 9 (1), 20, 2018
6332018
Machine learning prediction of cancer cell sensitivity to drugs based on genomic and chemical properties
MP Menden, F Iorio, M Garnett, U McDermott, CH Benes, PJ Ballester, ...
PLoS one 8 (4), e61318, 2013
5722013
Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition
M Sciacovelli, E Gonçalves, TI Johnson, VR Zecchini, ASH Da Costa, ...
Nature 537 (7621), 544-547, 2016
5702016
OmniPath: guidelines and gateway for literature-curated signaling pathway resources
D Türei, T Korcsmáros, J Saez-Rodriguez
Nature methods 13 (12), 966-967, 2016
5512016
Decoding myofibroblast origins in human kidney fibrosis
C Kuppe, MM Ibrahim, J Kranz, X Zhang, S Ziegler, J Perales-Patón, ...
Nature 589 (7841), 281-286, 2021
5252021
Towards a rigorous assessment of systems biology models: the DREAM3 challenges
RJ Prill, D Marbach, J Saez-Rodriguez, PK Sorger, LG Alexopoulos, ...
PloS one 5 (2), e9202, 2010
5182010
A methodology for the structural and functional analysis of signaling and regulatory networks
S Klamt, J Saez-Rodriguez, JA Lindquist, L Simeoni, ED Gilles
BMC bioinformatics 7, 1-26, 2006
4972006
Best practices for single-cell analysis across modalities
L Heumos, AC Schaar, C Lance, A Litinetskaya, F Drost, L Zappia, ...
Nature Reviews Genetics 24 (8), 550-572, 2023
4542023
Evaluation of methods for modeling transcription factor sequence specificity
MT Weirauch, A Cote, R Norel, M Annala, Y Zhao, TR Riley, ...
Nature biotechnology 31 (2), 126-134, 2013
4152013
Discrete logic modelling as a means to link protein signalling networks with functional analysis of mammalian signal transduction
J Saez‐Rodriguez, LG Alexopoulos, J Epperlein, R Samaga, ...
Molecular systems biology 5 (1), 331, 2009
4102009
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