The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease J Lamb, ED Crawford, D Peck, JW Modell, IC Blat, MJ Wrobel, J Lerner, ... science 313 (5795), 1929-1935, 2006 | 5200 | 2006 |
Cas9 specifies functional viral targets during CRISPR–Cas adaptation R Heler, P Samai, JW Modell, C Weiner, GW Goldberg, D Bikard, ... Nature 519 (7542), 199-202, 2015 | 538 | 2015 |
CRISPR–Cas systems exploit viral DNA injection to establish and maintain adaptive immunity JW Modell, W Jiang, LA Marraffini Nature 544 (7648), 101-104, 2017 | 154 | 2017 |
A DNA damage checkpoint in Caulobacter crescentus inhibits cell division through a direct interaction with FtsW JW Modell, AC Hopkins, MT Laub Genes & development 25 (12), 1328-1343, 2011 | 140 | 2011 |
A DNA Damage-Induced, SOS-Independent Checkpoint Regulates Cell Division in Caulobacter crescentus JW Modell, TK Kambara, BS Perchuk, MT Laub PLoS biology 12 (10), e1001977, 2014 | 114 | 2014 |
Chordin is required for neural but not axial development in sea urchin embryos CA Bradham, C Oikonomou, A Kühn, AB Core, JW Modell, DR McClay, ... Developmental biology 328 (2), 221-233, 2009 | 73 | 2009 |
A natural single-guide RNA repurposes Cas9 to autoregulate CRISPR-Cas expression RE Workman, T Pammi, BTK Nguyen, LW Graeff, E Smith, SM Sebald, ... Cell 184 (3), 675-688. e19, 2021 | 52 | 2021 |
Incomplete prophage tolerance by type III-A CRISPR-Cas systems reduces the fitness of lysogenic hosts GW Goldberg, EA McMillan, A Varble, JW Modell, P Samai, W Jiang, ... Nature communications 9 (1), 61, 2018 | 41 | 2018 |
Cleavage of viral DNA by restriction endonucleases stimulates the type II CRISPR-Cas immune response P Maguin, A Varble, JW Modell, LA Marraffini Molecular cell 82 (5), 907-919. e7, 2022 | 30 | 2022 |
Viral recombination systems limit CRISPR-Cas targeting through the generation of escape mutations AA Hossain, J McGinn, AJ Meeske, JW Modell, LA Marraffini Cell host & microbe 29 (10), 1482-1495. e12, 2021 | 15 | 2021 |
Prophage-like gene transfer agents promote Caulobacter crescentus survival and DNA repair during stationary phase K Gozzi, NT Tran, JW Modell, TBK Le, MT Laub PLoS biology 20 (11), e3001790, 2022 | 11 | 2022 |
Mitochondrial gradients and p38 activity in early sea urchin embryos JW Modell, CA Bradham Molecular reproduction and development 78 (4), 225-225, 2011 | 5 | 2011 |
Anti-CRISPR proteins trigger a burst of CRISPR-Cas9 expression that enhances phage defense RE Workman, MJ Stoltzfus, NC Keith, CW Euler, J Bondy-Denomy, ... Cell Reports 43 (3), 2024 | 2 | 2024 |
A DNA Damage-Induced JW Modell, TK Kambara, BS Perchuk, MT Laub SOS-Independent Checkpoint Regulates Cell Division in Caulobacter crescentus …, 2014 | 2 | 2014 |
about cmap J Lamb, ED Crawford, D Peck, JW Modell, IC Blat, MJ Wrobel, J Lerner, ... Science 313, 1929-1935, 2006 | 2 | 2006 |
A dynamic subpopulation of CRISPR-Cas overexpressers allows Streptococcus pyogenes to rapidly respond to phage MJ Stoltzfus, RE Workman, NC Keith, JW Modell bioRxiv, 2024.01. 11.575229, 2024 | | 2024 |
Regulatory pathways controlling cell division after DNA damage in Caulobacter crescentus JW Modell Massachusetts Institute of Technology, 2013 | | 2013 |