Erik Fredlund
Erik Fredlund
Dept. Oncology-Pathology, Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden
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Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development
P Kucharzewska, HC Christianson, JE Welch, KJ Svensson, E Fredlund, ...
Proceedings of the National Academy of Sciences 110 (18), 7312-7317, 2013
Recruitment of HIF-1α and HIF-2α to common target genes is differentially regulated in neuroblastoma: HIF-2α promotes an aggressive phenotype
L Holmquist-Mengelbier, E Fredlund, T Löfstedt, R Noguera, S Navarro, ...
Cancer cell 10 (5), 413-423, 2006
GOBO: gene expression-based outcome for breast cancer online
M Ringnér, E Fredlund, J Häkkinen, Å Borg, J Staaf
PloS one 6 (3), e17911, 2011
Hypoxia-induced dedifferentiation of tumor cells–a mechanism behind heterogeneity and aggressiveness of solid tumors
H Axelson, E Fredlund, M Ovenberger, G Landberg, S Påhlman
Seminars in cell & developmental biology 16 (4-5), 554-563, 2005
The miR-17-92 microRNA cluster regulates multiple components of the TGF-β pathway in neuroblastoma
P Mestdagh, AK Boström, F Impens, E Fredlund, G Van Peer, ...
Molecular cell 40 (5), 762-773, 2010
The mutational landscapes of genetic and chemical models of Kras-driven lung cancer
PMK Westcott, KD Halliwill, MD To, M Rashid, AG Rust, TM Keane, ...
Nature 517 (7535), 489-492, 2015
Hypoxia-inducible factors 1 and 2 are important transcriptional effectors in primary macrophages experiencing hypoxia
HY Fang, R Hughes, C Murdoch, SB Coffelt, SK Biswas, AL Harris, ...
Blood, The Journal of the American Society of Hematology 114 (4), 844-859, 2009
Pericyte–fibroblast transition promotes tumor growth and metastasis
K Hosaka, Y Yang, T Seki, C Fischer, O Dubey, E Fredlund, J Hartman, ...
Proceedings of the National Academy of Sciences 113 (38), E5618-E5627, 2016
Hypoxia inducible factor-2α in cancer
T Löfstedt, E Fredlund, L Holmquist-Mengelbier, A Pietras, M Ovenberger, ...
Cell cycle 6 (8), 919-926, 2007
High Myc pathway activity and low stage of neuronal differentiation associate with poor outcome in neuroblastoma
E Fredlund, M Ringnér, JM Maris, S Påhlman
Proceedings of the National Academy of Sciences 105 (37), 14094-14099, 2008
SubCellBarCode: proteome-wide mapping of protein localization and relocalization
LM Orre, M Vesterlund, Y Pan, T Arslan, Y Zhu, AF Woodbridge, O Frings, ...
Molecular cell 73 (1), 166-182. e7, 2019
Molecular stratification of metastatic melanoma using gene expression profiling: Prediction of survival outcome and benefit from molecular targeted therapy
H Cirenajwis, H Ekedahl, M Lauss, K Harbst, A Carneiro, J Enoksson, ...
Oncotarget 6 (14), 12297, 2015
An integrative genomics screen uncovers ncRNA T-UCR functions in neuroblastoma tumours
P Mestdagh, E Fredlund, F Pattyn, A Rihani, T Van Maerken, J Vermeulen, ...
Oncogene 29 (24), 3583-3592, 2010
HIF-2α maintains an undifferentiated state in neural crest-like human neuroblastoma tumor-initiating cells
A Pietras, LM Hansford, AS Johnsson, E Bridges, J Sjölund, D Gisselsson, ...
Proceedings of the National Academy of Sciences 106 (39), 16805-16810, 2009
Hypoxia-inducible factor-2α correlates to distant recurrence and poor outcome in invasive breast cancer
K Helczynska, AM Larsson, L Holmquist Mengelbier, E Bridges, ...
Cancer research 68 (22), 9212-9220, 2008
MYCN-regulated microRNAs repress estrogen receptor-α (ESR1) expression and neuronal differentiation in human neuroblastoma
J Lovén, N Zinin, T Wahlström, I Müller, P Brodin, E Fredlund, U Ribacke, ...
Proceedings of the National Academy of Sciences 107 (4), 1553-1558, 2010
Breast cancer quantitative proteome and proteogenomic landscape
HJ Johansson, F Socciarelli, NM Vacanti, MH Haugen, Y Zhu, I Siavelis, ...
Nature communications 10 (1), 1600, 2019
MYCN/c-MYC-induced microRNAs repress coding gene networks associated with poor outcome in MYCN/c-MYC-activated tumors
P Mestdagh, E Fredlund, F Pattyn, JH Schulte, D Muth, J Vermeulen, ...
Oncogene 29 (9), 1394-1404, 2010
PARP1-and CTCF-mediated interactions between active and repressed chromatin at the lamina promote oscillating transcription
H Zhao, EG Sifakis, N Sumida, L Millán-Ariño, BA Scholz, JP Svensson, ...
Molecular cell 59 (6), 984-997, 2015
Stromal Hedgehog signalling is downregulated in colon cancer and its restoration restrains tumour growth
M Gerling, NVJA Büller, LM Kirn, S Joost, O Frings, B Englert, Å Bergström, ...
Nature communications 7 (1), 12321, 2016
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