Landscape of somatic mutations in 560 breast cancer whole-genome sequences S Nik-Zainal, H Davies, J Staaf, M Ramakrishna, D Glodzik, X Zou, ... Nature 534 (7605), 47-54, 2016 | 2324 | 2016 |
Pan-cancer analysis of whole genomes Nature 578 (7793), 82-93, 2020 | 1932* | 2020 |
HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures H Davies, D Glodzik, S Morganella, LR Yates, J Staaf, X Zou, ... Nature medicine 23 (4), 517-525, 2017 | 1023 | 2017 |
Cancer therapy shapes the fitness landscape of clonal hematopoiesis KL Bolton, RN Ptashkin, T Gao, L Braunstein, SM Devlin, D Kelly, M Patel, ... Nature genetics 52 (11), 1219-1226, 2020 | 526 | 2020 |
The topography of mutational processes in breast cancer genomes S Morganella, LB Alexandrov, D Glodzik, X Zou, H Davies, J Staaf, ... Nature communications 7 (1), 11383, 2016 | 288 | 2016 |
Genomic landscape and chronological reconstruction of driver events in multiple myeloma F Maura, N Bolli, N Angelopoulos, KJ Dawson, D Leongamornlert, ... Nature communications 10 (1), 3835, 2019 | 274 | 2019 |
Whole-genome sequencing of triple-negative breast cancers in a population-based clinical study J Staaf, D Glodzik, A Bosch, J Vallon-Christersson, C Reuterswärd, ... Nature medicine 25 (10), 1526-1533, 2019 | 262 | 2019 |
The genome as a record of environmental exposure S Nik-Zainal, JE Kucab, S Morganella, D Glodzik, LB Alexandrov, VM Arlt, ... Mutagenesis 30 (6), 763-770, 2015 | 254 | 2015 |
A practical framework and online tool for mutational signature analyses show intertissue variation and driver dependencies A Degasperi, TD Amarante, J Czarnecki, S Shooter, X Zou, D Glodzik, ... Nature cancer 1 (2), 249-263, 2020 | 217 | 2020 |
Plasma vitamin D concentration influences survival outcome after a diagnosis of colorectal cancer L Zgaga, E Theodoratou, SM Farrington, FVN Din, LY Ooi, D Glodzik, ... Journal of Clinical Oncology 32 (23), 2430-2439, 2014 | 197 | 2014 |
Whole-genome sequencing reveals breast cancers with mismatch repair deficiency H Davies, S Morganella, CA Purdie, SJ Jang, E Borgen, H Russnes, ... Cancer research 77 (18), 4755-4762, 2017 | 113 | 2017 |
Revealing the impact of structural variants in multiple myeloma EH Rustad, VD Yellapantula, D Glodzik, KH Maclachlan, B Diamond, ... Blood cancer discovery 1 (3), 258-273, 2020 | 108 | 2020 |
A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers D Glodzik, S Morganella, H Davies, PT Simpson, Y Li, X Zou, ... Nature genetics 49 (3), 341-348, 2017 | 95 | 2017 |
Functional patient-derived organoid screenings identify MCLA-158 as a therapeutic EGFR× LGR5 bispecific antibody with efficacy in epithelial tumors B Herpers, B Eppink, MI James, C Cortina, A Cañellas-Socias, SF Boj, ... Nature cancer 3 (4), 418-436, 2022 | 92 | 2022 |
Comprehensive molecular comparison of BRCA1 hypermethylated and BRCA1 mutated triple negative breast cancers D Glodzik, A Bosch, J Hartman, M Aine, J Vallon-Christersson, ... Nature communications 11 (1), 3747, 2020 | 82 | 2020 |
Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation AB Brinkman, S Nik-Zainal, F Simmer, FG Rodríguez-González, M Smid, ... Nature communications 10 (1), 1749, 2019 | 63 | 2019 |
Feasibility of whole genome and transcriptome profiling in pediatric and young adult cancers N Shukla, MF Levine, G Gundem, D Domenico, B Spitzer, N Bouvier, ... Nature communications 13 (1), 2485, 2022 | 44 | 2022 |
Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples MH Bailey, WU Meyerson, LJ Dursi, LB Wang, G Dong, WW Liang, ... Nature communications 11 (1), 4748, 2020 | 44 | 2020 |
Utility of non-rule-based visual matching as a strategy to allow novices to achieve skin lesion diagnosis RB Aldridge, D Glodzik, L Ballerini, RB Fisher, LR Jonathan Acta dermato-venereologica 91 (3), 279, 2011 | 35 | 2011 |
Short inverted repeats contribute to localized mutability in human somatic cells X Zou, S Morganella, D Glodzik, H Davies, Y Li, MR Stratton, S Nik-Zainal Nucleic Acids Research 45 (19), 11213-11221, 2017 | 34 | 2017 |