| A community-driven global reconstruction of human metabolism I Thiele, N Swainston, RMT Fleming, A Hoppe, S Sahoo, MK Aurich, ... Nature biotechnology 31 (5), 419-425, 2013 | 1210 | 2013 |
| Bioconda: sustainable and comprehensive software distribution for the life sciences B Grüning, R Dale, A Sjödin, BA Chapman, J Rowe, CH Tomkins-Tinch, ... Nature methods 15 (7), 475-476, 2018 | 1110 | 2018 |
| Genome-scale metabolic modelling of hepatocytes reveals serine deficiency in patients with non-alcoholic fatty liver disease A Mardinoglu, R Agren, C Kampf, A Asplund, M Uhlen, J Nielsen Nature communications 5 (1), 3083, 2014 | 582 | 2014 |
| Reconstruction of genome-scale active metabolic networks for 69 human cell types and 16 cancer types using INIT R Agren, S Bordel, A Mardinoglu, N Pornputtapong, I Nookaew, J Nielsen PLoS computational biology 8 (5), e1002518, 2012 | 498 | 2012 |
| The RAVEN Toolbox and Its Use for Generating a Genome-scale Metabolic Model for Penicillium chrysogenum R Agren, L Liu, S Shoaie, W Vongsangnak, I Nookaew, J Nielsen PLOS Computational Biology 9 (3), e1002980, 2013 | 469 | 2013 |
| Identification of anticancer drugs for hepatocellular carcinoma through personalized genome‐scale metabolic modeling R Agren, A Mardinoglu, A Asplund, C Kampf, M Uhlen, J Nielsen Molecular systems biology 10 (3), 721, 2014 | 392 | 2014 |
| RAVEN 2.0: A versatile toolbox for metabolic network reconstruction and a case study on Streptomyces coelicolor H Wang, S Marcišauskas, BJ Sánchez, I Domenzain, D Hermansson, ... PLoS computational biology 14 (10), e1006541, 2018 | 333 | 2018 |
| Integration of clinical data with a genome-scale metabolic model of the human adipocyte A Mardinoglu, R Agren, C Kampf, A Asplund, I Nookaew, P Jacobson, ... Molecular Systems Biology 9 (1), 2013 | 262 | 2013 |
| Sampling the solution space in genome-scale metabolic networks reveals transcriptional regulation in key enzymes S Bordel, R Agren, J Nielsen PLoS computational biology 6 (7), e1000859, 2010 | 196 | 2010 |
| Genome-scale metabolic reconstructions of Pichia stipitis and Pichia pastoris and in silico evaluation of their potentials L Caspeta, S Shoaie, R Agren, I Nookaew, J Nielsen BMC systems biology 6, 1-14, 2012 | 141 | 2012 |
| BioMet Toolbox: genome-wide analysis of metabolism M Cvijovic, R Olivares-Hernï¿ ½ndez, R Agren, N Dahr, W Vongsangnak, ... Nucleic acids research 38 (suppl_2), W144-W149, 2010 | 129 | 2010 |
| Use of genome-scale metabolic models for understanding microbial physiology L Liu, R Agren, S Bordel, J Nielsen FEBS letters 584 (12), 2556-2564, 2010 | 109 | 2010 |
| Metabolic Needs and Capabilities of Toxoplasma gondii through Combined Computational and Experimental Analysis S Tymoshenko, RD Oppenheim, R Agren, J Nielsen, D Soldati-Favre, ... PLoS computational biology 11 (5), e1004261, 2015 | 101 | 2015 |
| Genome-scale modeling enables metabolic engineering of Saccharomyces cerevisiae for succinic acid production R Agren, JM Otero, J Nielsen Journal of Industrial Microbiology and Biotechnology 40 (7), 735-747, 2013 | 96 | 2013 |
| ATAC-seq reveals alterations in open chromatin in pancreatic islets from subjects with type 2 diabetes M Bysani, R Agren, C Davegårdh, P Volkov, T Rönn, P Unneberg, ... Scientific reports 9 (1), 7785, 2019 | 60 | 2019 |
| Archaeal community changes in Lateglacial lake sediments: Evidence from ancient DNA E Ahmed, L Parducci, P Unneberg, R Ågren, F Schenk, JE Rattray, L Han, ... Quaternary Science Reviews 181, 19-29, 2018 | 53 | 2018 |
| MEMOSys: Bioinformatics platform for genome-scale metabolic models S Pabinger, R Rader, R Agren, J Nielsen, Z Trajanoski BMC systems biology 5, 1-9, 2011 | 47 | 2011 |
| Metabolome dynamics of diapause in the butterfly Pieris napi: distinguishing maintenance, termination and post-diapause phases P Lehmann, P Pruisscher, V Koštál, M Moos, P Šimek, S Nylin, R Agren, ... Journal of Experimental Biology 221 (2), jeb169508, 2018 | 42 | 2018 |
| In vivo screen identifies a SIK inhibitor that induces β cell proliferation through a transient UPR J Charbord, L Ren, RB Sharma, A Johansson, R Ågren, L Chu, D Tworus, ... Nature metabolism 3 (5), 682-700, 2021 | 32 | 2021 |
| The landscape of ancient human pathogens in Eurasia from the Stone Age to historical times M Sikora, E Canteri, A Fernandez-Guerra, N Oskolkov, R Ågren, ... bioRxiv, 2023.10. 06.561165, 2023 | 3 | 2023 |
Jens NielsenProfessor in Systems Biology, Chalmers University of Technology, SwedenVerified email at chalmers.se
