IRE1 plays an essential role in ER stress-mediated aggregation of mutant huntingtin via the inhibition of autophagy flux H Lee, JY Noh, Y Oh, Y Kim, JW Chang, CW Chung, ST Lee, M Kim, ... Human molecular genetics 21 (1), 101-114, 2012 | 176 | 2012 |
mRNA 3′-UTR shortening is a molecular signature of mTORC1 activation JW Chang, W Zhang, HS Yeh, EP De Jong, S Jun, KH Kim, SS Bae, ... Nature communications 6 (1), 7218, 2015 | 89 | 2015 |
Neuronal vulnerability of CLN3 deletion to calcium-induced cytotoxicity is mediated by calsenilin JW Chang, H Choi, HJ Kim, DG Jo, YJ Jeon, JY Noh, WJ Park, YK Jung Human molecular genetics 16 (3), 317-326, 2007 | 73 | 2007 |
Calcium binding of ARC mediates regulation of caspase 8 and cell death DG Jo, JI Jun, JW Chang, YM Hong, S Song, DH Cho, SM Shim, HJ Lee, ... Molecular and cellular biology, 2004 | 72 | 2004 |
SCAMP5 links endoplasmic reticulum stress to the accumulation of expanded polyglutamine protein aggregates via endocytosis inhibition JY Noh, H Lee, S Song, NS Kim, W Im, M Kim, H Seo, CW Chung, ... Journal of Biological Chemistry 284 (17), 11318-11325, 2009 | 64 | 2009 |
Peroxiredoxin 6 interferes with TRAIL-induced death-inducing signaling complex formation by binding to death effector domain caspase H Choi, JW Chang, YK Jung Cell Death & Differentiation 18 (3), 405-414, 2011 | 51 | 2011 |
Lithium rescues the impaired autophagy process in CbCln3Δex7/8/Δex7/8 cerebellar cells and reduces neuronal vulnerability to cell death via IMPase inhibition JW Chang, H Choi, SL Cotman, YK Jung Journal of neurochemistry 116 (4), 659-668, 2011 | 49 | 2011 |
Protection of cardiomyocytes from ischemic/hypoxic cell death via Drbp1 and pMe2GlyDH in cardio-specific ARC transgenic mice JO Pyo, J Nah, HJ Kim, JW Chang, YW Song, DK Yang, DG Jo, HR Kim, ... Journal of Biological Chemistry 283 (45), 30707-30714, 2008 | 48 | 2008 |
BECN1/Beclin 1 is recruited into lipid rafts by prion to activate autophagy in response to amyloid β 42 J Nah, JO Pyo, S Jung, SM Yoo, TI Kam, JW Chang, J Han, SSA An, ... autophagy 9 (12), 2009-2021, 2013 | 47 | 2013 |
Alternative polyadenylation in human diseases JW Chang, HS Yeh, J Yong Endocrinology and Metabolism 32 (4), 413-421, 2017 | 45 | 2017 |
Contribution of presenilin/γ-secretase to calsenilin-mediated apoptosis DG Jo, JW Chang, HS Hong, I Mook-Jung, YK Jung Biochemical and biophysical research communications 305 (1), 62-66, 2003 | 40 | 2003 |
An integrative model for alternative polyadenylation, IntMAP, delineates mTOR-modulated endoplasmic reticulum stress response JW Chang, W Zhang, HS Yeh, M Park, C Yao, Y Shi, R Kuang, J Yong Nucleic acids research 46 (12), 5996-6008, 2018 | 33 | 2018 |
Down‐regulation of ARC contributes to vulnerability of hippocampal neurons to ischemia/hypoxia YM Hong, DG Jo, JY Lee, JW Chang, JH Nam, JY Noh, JY Koh, YK Jung FEBS letters 543 (1-3), 170-173, 2003 | 32 | 2003 |
Network-based isoform quantification with RNA-seq data for cancer transcriptome analysis W Zhang, JW Chang, L Lin, K Minn, B Wu, J Chien, J Yong, H Zheng, ... PLoS computational biology 11 (12), e1004465, 2015 | 22 | 2015 |
Engineering CD70-directed CAR-NK cells for the treatment of hematological and solid malignancies E Choi, JW Chang, J Krueger, WS Lahr, E Pomeroy, M Walsh, ... Blood 138, 1691, 2021 | 20 | 2021 |
mTOR-regulated U2af1 tandem exon splicing specifies transcriptome features for translational control JW Chang, HS Yeh, M Park, L Erber, J Sun, S Cheng, AM Bui, NA Fahmi, ... Nucleic acids research 47 (19), 10373-10387, 2019 | 18 | 2019 |
Characterization of subcellular localization and Ca2+ modulation of calsenilin/DREAM/KChIP3 HN Woo, JW Chang, YH Choi, AR Gwon, YK Jung, DG Jo Neuroreport 19 (12), 1193-1197, 2008 | 17 | 2008 |
Non-Viral Engineering of CAR-NK and CAR-T cells using the Tc Buster Transposon System™ EJ Pomeroy, WS Lahr, JW Chang, J Krueger, BJ Wick, NJ Slipek, ... BioRxiv, 2021.08. 02.454772, 2021 | 15 | 2021 |
As-quant: Detection and visualization of alternative splicing events with rna-seq data NA Fahmi, H Nassereddeen, J Chang, M Park, H Yeh, J Sun, D Fan, ... International journal of molecular sciences 22 (9), 4468, 2021 | 15 | 2021 |
Identification of glucose-6-phosphate transporter as a key regulator functioning at the autophagy initiation step HH Ahn, Y Oh, H Lee, WJ Lee, JW Chang, HK Pyo, YK Jung FEBS letters 589 (16), 2100-2109, 2015 | 15 | 2015 |