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A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence J Kaplon, L Zheng, K Meissl, B Chaneton, VA Selivanov, G Mackay, ... Nature 498 (7452), 109-112, 2013 | 655 | 2013 |
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Metabolomics enables precision medicine:“a white paper, community perspective” RD Beger, W Dunn, MA Schmidt, SS Gross, JA Kirwan, M Cascante, ... Metabolomics 12, 1-15, 2016 | 550 | 2016 |
Targeting cell cycle regulation in cancer therapy S Diaz-Moralli, M Tarrado-Castellarnau, A Miranda, M Cascante Pharmacology & therapeutics 138 (2), 255-271, 2013 | 423 | 2013 |
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Valorization of grape (Vitis vinifera) byproducts. Antioxidant and biological properties of polyphenolic fractions differing in procyanidin composition and flavonol content JL Torres, B Varela, MT García, J Carilla, C Matito, JJ Centelles, ... Journal of agricultural and food chemistry 50 (26), 7548-7555, 2002 | 337 | 2002 |
The puzzle of the Krebs citric acid cycle: assembling the pieces of chemically feasible reactions, and opportunism in the design of metabolic pathways during evolution E Meléndez-Hevia, TG Waddell, M Cascante Journal of Molecular Evolution 43 (3), 293-303, 1996 | 297 | 1996 |
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Maslinic acid, a natural triterpene from< i> Olea europaea</i> L., induces apoptosis in HT29 human colon-cancer cells via the mitochondrial apoptotic pathway FJ Reyes-Zurita, EE Rufino-Palomares, JA Lupiáñez, M Cascante Cancer Letters 273 (1), 44-54, 2009 | 228 | 2009 |
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Relationships between inhibition constants, inhibitor concentrations for 50% inhibition and types of inhibition: new ways of analysing data. A Cortés, M Cascante, ML Cárdenas, A Cornish-Bowden Biochemical Journal 357 (Pt 1), 263, 2001 | 213 | 2001 |
From correlation to causation: analysis of metabolomics data using systems biology approaches A Rosato, L Tenori, M Cascante, PR De Atauri Carulla, ... Metabolomics 14, 1-20, 2018 | 200 | 2018 |
Reactive oxygen species production by forward and reverse electron fluxes in the mitochondrial respiratory chain VA Selivanov, TV Votyakova, VN Pivtoraiko, J Zeak, T Sukhomlin, ... PLoS computational biology 7 (3), e1001115, 2011 | 187 | 2011 |
Metabolic profiling of cell growth and death in cancer: applications in drug discovery LG Boros, M Cascante, WNP Lee Drug discovery today 7 (6), 364-372, 2002 | 185 | 2002 |
Novel semisynthetic derivatives of betulin and betulinic acid with cytotoxic activity RC Santos, JAR Salvador, S Marín, M Cascante Bioorganic & medicinal chemistry 17 (17), 6241-6250, 2009 | 174 | 2009 |
Metabolic strategy of boar spermatozoa revealed by a metabolomic characterization S Marin, K Chiang, S Bassilian, WNP Lee, LG Boros, ... FEBS letters 554 (3), 342-346, 2003 | 168 | 2003 |