Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease JC Lambert, CA Ibrahim-Verbaas, D Harold, AC Naj, R Sims, ... Nature genetics 45 (12), 1452-1458, 2013 | 4608 | 2013 |
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ... Nature genetics 51 (3), 414-430, 2019 | 2481 | 2019 |
New insights into the genetic etiology of Alzheimer’s disease and related dementias C Bellenguez, F Küçükali, IE Jansen, L Kleineidam, S Moreno-Grau, ... Nature genetics 54 (4), 412-436, 2022 | 1356 | 2022 |
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ... Nature genetics 49 (9), 1373-1384, 2017 | 964 | 2017 |
APOE and Alzheimer disease: a major gene with semi-dominant inheritance E Genin, D Hannequin, D Wallon, K Sleegers, M Hiltunen, O Combarros, ... Molecular psychiatry 16 (9), 903-907, 2011 | 808 | 2011 |
APP, PSEN1, and PSEN2 mutations in early-onset Alzheimer disease: A genetic screening study of familial and sporadic cases HM Lanoiselée, G Nicolas, D Wallon, A Rovelet-Lecrux, M Lacour, ... PLoS medicine 14 (3), e1002270, 2017 | 568 | 2017 |
High frequency of potentially pathogenic SORL1 mutations in autosomal dominant early-onset Alzheimer disease C Pottier, D Hannequin, S Coutant, A Rovelet-Lecrux, D Wallon, ... Molecular psychiatry 17 (9), 875-879, 2012 | 304 | 2012 |
A novel Alzheimer disease locus located near the gene encoding tau protein G Jun, CA Ibrahim-Verbaas, M Vronskaya, JC Lambert, J Chung, AC Naj, ... Molecular psychiatry 21 (1), 108-117, 2016 | 301 | 2016 |
European Alzheimer’s Disease Initiative (EADI); Genetic and Environmental Risk in Alzheimer’s Disease; Alzheimer’s Disease Genetic Consortium; Cohorts for Heart and Aging … JC Lambert, CA Ibrahim-Verbaas, D Harold, AC Naj, R Sims, ... Nat Genet 45 (12), 1452-1458, 2013 | 297 | 2013 |
A trial of gantenerumab or solanezumab in dominantly inherited Alzheimer’s disease S Salloway, M Farlow, E McDade, DB Clifford, G Wang, JJ Llibre-Guerra, ... Nature medicine 27 (7), 1187-1196, 2021 | 289 | 2021 |
Phenotypic spectrum of probable and genetically-confirmed idiopathic basal ganglia calcification G Nicolas, C Pottier, C Charbonnier, L Guyant-Maréchal, I Le Ber, ... Brain 136 (11), 3395-3407, 2013 | 229 | 2013 |
Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores I De Rojas, S Moreno-Grau, N Tesi, B Grenier-Boley, V Andrade, ... Nature communications 12 (1), 3417, 2021 | 227 | 2021 |
TREM2 R47H Variant as a Risk Factor for Early-Onset Alzheimer's Disease C Pottier, D Wallon, S Rousseau, A Rovelet-Lecrux, AC Richard, ... Journal of Alzheimer’s Disease 35 (1), 45-49, 2013 | 180 | 2013 |
Contribution to Alzheimer's disease risk of rare variants in TREM2, SORL1, and ABCA7 in 1779 cases and 1273 controls C Bellenguez, C Charbonnier, B Grenier-Boley, O Quenez, K Le Guennec, ... Neurobiology of aging 59, 220. e1-220. e9, 2017 | 179 | 2017 |
Convergent genetic and expression data implicate immunity in Alzheimer's disease International Genomics of Alzheimer's Disease Consortium (IGAP), ... Alzheimer's & Dementia 11 (6), 658-671, 2015 | 160 | 2015 |
Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease V Escott-Price, C Bellenguez, LS Wang, SH Choi, D Harold, L Jones, ... PloS one 9 (6), e94661, 2014 | 150 | 2014 |
Plasma amyloid levels within the Alzheimer's process and correlations with central biomarkers O Hanon, JS Vidal, S Lehmann, S Bombois, B Allinquant, JM Tréluyer, ... Alzheimer's & Dementia 14 (7), 858-868, 2018 | 142 | 2018 |
SORL1 rare variants: a major risk factor for familial early-onset Alzheimer’s disease G Nicolas, C Charbonnier, D Wallon, O Quenez, C Bellenguez, ... Molecular psychiatry 21 (6), 831-836, 2016 | 141 | 2016 |
The French series of autosomal dominant early onset Alzheimer's disease cases: mutation spectrum and cerebrospinal fluid biomarkers D Wallon, S Rousseau, A Rovelet-Lecrux, M Quillard-Muraine, ... Journal of Alzheimer’s disease 30 (4), 847-856, 2012 | 137 | 2012 |
Seizures in dominantly inherited Alzheimer disease A Zarea, C Charbonnier, A Rovelet-Lecrux, G Nicolas, S Rousseau, ... Neurology 87 (9), 912-919, 2016 | 116 | 2016 |