| The hematopoietic stem cell niche: from embryo to adult X Gao, C Xu, N Asada, PS Frenette Development 145 (2), dev139691, 2018 | 216 | 2018 |
| Cis-element mutated in GATA2-dependent immunodeficiency governs hematopoiesis and vascular integrity KD Johnson, AP Hsu, MJ Ryu, J Wang, X Gao, ME Boyer, Y Liu, Y Lee, ... The Journal of clinical investigation 122 (10), 3692-3704, 2012 | 215 | 2012 |
| Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow C Xu, X Gao, Q Wei, F Nakahara, SE Zimmerman, J Mar, PS Frenette Nature communications 9 (1), 2449, 2018 | 185 | 2018 |
| Gata2 cis-element is required for hematopoietic stem cell generation in the mammalian embryo X Gao, KD Johnson, YI Chang, ME Boyer, CN Dewey, J Zhang, ... Journal of Experimental Medicine 210 (13), 2833-2842, 2013 | 170 | 2013 |
| The GATA factor revolution in hematology KR Katsumura, EH Bresnick, GATA Factor Mechanisms Group Blood, The Journal of the American Society of Hematology 129 (15), 2092-2102, 2017 | 149 | 2017 |
| Nociceptive nerves regulate haematopoietic stem cell mobilization X Gao, D Zhang, C Xu, H Li, KM Caron, PS Frenette Nature 589 (7843), 591-596, 2021 | 114 | 2021 |
| The role of polymeric immunoglobulin receptor in inflammation-induced tumor metastasis of human hepatocellular carcinoma J Ai, Q Tang, Y Wu, Y Xu, T Feng, R Zhou, Y Chen, X Gao, Q Zhu, X Yue, ... Journal of the National Cancer Institute 103 (22), 1696-1712, 2011 | 98 | 2011 |
| Cis-regulatory mechanisms governing stem and progenitor cell transitions KD Johnson, G Kong, X Gao, YI Chang, KJ Hewitt, R Sanalkumar, ... Science advances 1 (8), e1500503, 2015 | 71 | 2015 |
| Integrating enhancer mechanisms to establish a hierarchical blood development program C Mehta, KD Johnson, X Gao, IM Ong, KR Katsumura, SC McIver, ... Cell reports 20 (12), 2966-2979, 2017 | 57 | 2017 |
| Mechanism governing a stem cell-generating cis-regulatory element R Sanalkumar, KD Johnson, X Gao, ME Boyer, YI Chang, KJ Hewitt, ... Proceedings of the National Academy of Sciences 111 (12), E1091-E1100, 2014 | 53 | 2014 |
| The microbiota regulates hematopoietic stem cell fate decisions by controlling iron availability in bone marrow D Zhang, X Gao, H Li, DK Borger, Q Wei, E Yang, C Xu, S Pinho, ... Cell Stem Cell 29 (2), 232-247. e7, 2022 | 52 | 2022 |
| Discovery of novel c-Met kinase inhibitors bearing a thieno [2, 3-d] pyrimidine or furo [2, 3-d] pyrimidine scaffold A Zhao, X Gao, Y Wang, J Ai, Y Wang, Y Chen, M Geng, A Zhang Bioorganic & medicinal chemistry 19 (13), 3906-3918, 2011 | 43 | 2011 |
| p53 −/− synergizes with enhanced NrasG12D signaling to transform megakaryocyte-erythroid progenitors in acute myeloid leukemia J Zhang, G Kong, A Rajagopalan, L Lu, J Song, M Hussaini, X Zhang, ... Blood, The Journal of the American Society of Hematology 129 (3), 358-370, 2017 | 31 | 2017 |
| Asxl1 loss cooperates with oncogenic Nras in mice to reprogram the immune microenvironment and drive leukemic transformation X You, F Liu, M Binder, A Vedder, T Lasho, Z Wen, X Gao, E Flietner, ... Blood, The Journal of the American Society of Hematology 139 (7), 1066-1079, 2022 | 26 | 2022 |
| GATA factor-G-protein-coupled receptor circuit suppresses hematopoiesis X Gao, T Wu, KD Johnson, JL Lahvic, EA Ranheim, LI Zon, EH Bresnick Stem cell reports 6 (3), 368-382, 2016 | 24 | 2016 |
| The hematopoietic stem and progenitor cell cistrome: GATA factor-dependent cis-regulatory mechanisms KJ Hewitt, KD Johnson, X Gao, S Keles, EH Bresnick Current topics in developmental biology 118, 45-76, 2016 | 23 | 2016 |
| Snai2 maintains bone marrow niche cells by repressing osteopontin expression Q Wei, F Nakahara, N Asada, D Zhang, X Gao, C Xu, A Alfieri, NP Brodin, ... Developmental cell 53 (5), 503-513. e5, 2020 | 18 | 2020 |
| Dissecting regulatory mechanisms using mouse fetal liver-derived erythroid cells SC McIver, KJ Hewitt, X Gao, C Mehta, J Zhang, EH Bresnick Erythropoiesis: Methods and Protocols, 67-89, 2018 | 17 | 2018 |
| Tet-mediated DNA demethylation regulates specification of hematopoietic stem and progenitor cells during mammalian embryogenesis L Ma, Q Tang, X Gao, J Lee, R Lei, M Suzuki, D Zheng, K Ito, PS Frenette, ... Science advances 8 (9), eabm3470, 2022 | 16 | 2022 |
| Olinciguat, a stimulator of soluble guanylyl cyclase, attenuates inflammation, vaso‐occlusion and nephropathy in mouse models of sickle cell disease B Tchernychev, H Li, SK Lee, X Gao, R Ramanarasimhaiah, G Liu, ... British journal of pharmacology 178 (17), 3463-3475, 2021 | 15 | 2021 |
Sanalkumar RajendranCHUV, SwitzerlandVerified email at chuv.ch
