Principal components analysis corrects for stratification in genome-wide association studies AL Price, NJ Patterson, RM Plenge, ME Weinblatt, NA Shadick, D Reich Nature genetics 38 (8), 904-909, 2006 | 11443 | 2006 |
Genetics of rheumatoid arthritis contributes to biology and drug discovery Y Okada, D Wu, G Trynka, T Raj, C Terao, K Ikari, Y Kochi, K Ohmura, ... Nature 506 (7488), 376-381, 2014 | 2600 | 2014 |
FinnGen provides genetic insights from a well-phenotyped isolated population MI Kurki, J Karjalainen, P Palta, TP Sipilä, K Kristiansson, KM Donner, ... Nature 613 (7944), 508-518, 2023 | 1751 | 2023 |
Genomic atlas of the human plasma proteome BB Sun, JC Maranville, JE Peters, D Stacey, JR Staley, J Blackshaw, ... Nature 558 (7708), 73-79, 2018 | 1661 | 2018 |
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci EA Stahl, S Raychaudhuri, EF Remmers, G Xie, S Eyre, BP Thomson, Y Li, ... Nature genetics 42 (6), 508-514, 2010 | 1605 | 2010 |
STAT4 and the Risk of Rheumatoid Arthritis and Systemic Lupus Erythematosus EF Remmers, RM Plenge, AT Lee, RR Graham, G Hom, TW Behrens, ... New England Journal of Medicine 357 (10), 977-986, 2007 | 1342 | 2007 |
JAK and STAT signaling molecules in immunoregulation and immune-mediated disease JJ O'Shea, R Plenge Immunity 36 (4), 542-550, 2012 | 1185 | 2012 |
The major genetic determinants of HIV-1 control affect HLA class I peptide presentation International HIV Controllers Study Science 330 (6010), 1551-1557, 2010 | 1143 | 2010 |
Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis S Raychaudhuri, C Sandor, EA Stahl, J Freudenberg, HS Lee, X Jia, ... Nature genetics 44 (3), 291-296, 2012 | 1112 | 2012 |
TRAF1–C5 as a risk locus for rheumatoid arthritis—a genomewide study RM Plenge, M Seielstad, L Padyukov, AT Lee, EF Remmers, B Ding, ... New England Journal of Medicine 357 (12), 1199-1209, 2007 | 1062 | 2007 |
de VN, Worthington J, Seielstad M, Toes RE, Karlson EW, Begovich AB, Klareskog L, Gregersen PK, Daly MJ, Plenge RM: Common variants at CD40 and other loci confer risk of … S Raychaudhuri, EF Remmers, AT Lee, R Hackett, C Guiducci, NP Burtt, ... Nat Genet 40, 1216-1223, 2008 | 918* | 2008 |
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations A Köttgen, E Albrecht, A Teumer, V Vitart, J Krumsiek, C Hundertmark, ... Nature genetics 45 (2), 145-154, 2013 | 916 | 2013 |
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis S Eyre, J Bowes, D Diogo, A Lee, A Barton, P Martin, A Zhernakova, ... Nature genetics 44 (12), 1336-1340, 2012 | 788 | 2012 |
Defining the role of the MHC in autoimmunity: a review and pooled analysis MMA Fernando, CR Stevens, EC Walsh, PL De Jager, P Goyette, ... PLoS genetics 4 (4), e1000024, 2008 | 777 | 2008 |
A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus RR Graham, SV Kozyrev, EC Baechler, MVPL Reddy, RM Plenge, ... Nature genetics 38 (5), 550-555, 2006 | 768 | 2006 |
Replication of putative candidate-gene associations with rheumatoid arthritis in> 4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4 … RM Plenge, L Padyukov, EF Remmers, S Purcell, AT Lee, EW Karlson, ... American journal of human genetics 77 (6), 1044, 2005 | 741 | 2005 |
Validating therapeutic targets through human genetics RM Plenge, EM Scolnick, D Altshuler Nature reviews Drug discovery 12 (8), 581-594, 2013 | 689 | 2013 |
Two independent alleles at 6q23 associated with risk of rheumatoid arthritis RM Plenge, C Cotsapas, L Davies, AL Price, PIW De Bakker, J Maller, ... Nature genetics 39 (12), 1477-1482, 2007 | 681 | 2007 |
Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus RR Graham, C Cotsapas, L Davies, R Hackett, CJ Lessard, JM Leon, ... Nature genetics 40 (9), 1059-1061, 2008 | 671 | 2008 |
Gene-gene and gene-environment interactions involving HLA-DRB1, PTPN22, and smoking in two subsets of rheumatoid arthritis H Källberg, L Padyukov, RM Plenge, J Rönnelid, PK Gregersen, ... American journal of human genetics 80 (5), 867, 2007 | 623 | 2007 |