Tim U. Krohne
Tim U. Krohne
Dept. of Ophthalmology, Univ. of Cologne, Germany
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Intraocular pharmacokinetics of bevacizumab after a single intravitreal injection in humans
TU Krohne, N Eter, FG Holz, CH Meyer
American journal of ophthalmology 146 (4), 508-512, 2008
TNF-α mediated apoptosis plays an important role in the development of early diabetic retinopathy and long-term histopathological alterations
AM Joussen, S Doehmen, ML Le, K Koizumi, S Radetzky, TU Krohne, ...
Molecular vision 15, 1418, 2009
Intraocular pharmacokinetics of ranibizumab following a single intravitreal injection in humans
TU Krohne, Z Liu, FG Holz, CH Meyer
American journal of ophthalmology 154 (4), 682-686. e2, 2012
Astrocyte hypoxic response is essential for pathological but not developmental angiogenesis of the retina
A Weidemann, TU Krohne, E Aguilar, T Kurihara, N Takeda, MI Dorrell, ...
Glia 58 (10), 1177-1185, 2010
Effects of lipid peroxidation products on lipofuscinogenesis and autophagy in human retinal pigment epithelial cells
TU Krohne, NK Stratmann, J Kopitz, FG Holz
Experimental eye research 90 (3), 465-471, 2010
Effects of lipid peroxidation-related protein modifications on RPE lysosomal functions and POS phagocytosis
E Kaemmerer, F Schutt, TU Krohne, FG Holz, J Kopitz
Investigative ophthalmology & visual science 48 (3), 1342-1347, 2007
Mouse α-fetoprotein–specific DNA-based immunotherapy of hepatocellular carcinoma leads to tumor regression in mice
CF Grimm, D Ortmann, L Mohr, S Michalak, TU Krohne, S Meckel, ...
Gastroenterology 119 (4), 1104-1112, 2000
Comparing alternative ranibizumab dosages for safety and efficacy in retinopathy of prematurity: a randomized clinical trial
A Stahl, TU Krohne, N Eter, I Oberacher-Velten, R Guthoff, S Meltendorf, ...
JAMA pediatrics 172 (3), 278-286, 2018
Intraocular pharmacokinetics after a single intravitreal injection of 1.5 mg versus 3.0 mg of bevacizumab in humans
CH Meyer, TU Krohne, FG Holz
Retina 31 (9), 1877-1884, 2011
Generation of Retinal Pigment Epithelial Cells from Small Molecules and OCT4 Reprogrammed Human Induced Pluripotent Stem Cells
TU Krohne, PD Westenskow, T Kurihara, DF Friedlander, M Lehmann, ...
Stem cells translational medicine 1 (2), 96-109, 2012
Lipid peroxidation products reduce lysosomal protease activities in human retinal pigment epithelial cells via two different mechanisms of action
TU Krohne, E Kaemmerer, FG Holz, J Kopitz
Experimental eye research 90 (2), 261-266, 2010
Gene therapy of hepatocellular carcinoma in vitro and in vivo in nude mice by adenoviral transfer of the escherichia coli purine nucleoside phosphorylase gene
L Mohr, S Shankara, SK Yoon, TU Krohne, M Geissler, B Roberts, ...
Hepatology 31 (3), 606-614, 2000
Modulation of three key innate immune pathways for the most common retinal degenerative diseases
I Akhtar‐Schäfer, L Wang, TU Krohne, H Xu, T Langmann
EMBO molecular medicine 10 (10), e8259, 2018
Light induces NLRP3 inflammasome activation in retinal pigment epithelial cells via lipofuscin-mediated photooxidative damage
C Brandstetter, LKM Mohr, E Latz, FG Holz, TU Krohne
Journal of Molecular Medicine 93, 905-916, 2015
Mechanisms of cell death induced by suicide genes encoding purine nucleoside phosphorylase and thymidine kinase in human hepatocellular carcinoma cells in vitro
TU Krohne, S Shankara, M Geissler, BL Roberts, JR Wands, HE Blum, ...
Hepatology 34 (3), 511-518, 2001
Retinal injury following laser pointer exposure: a systematic review and case series
J Birtel, WM Harmening, TU Krohne, FG Holz, PC Issa, P Herrmann
Deutsches Ärzteblatt International 114 (49), 831, 2017
In-depth mass spectrometric mapping of the human vitreous proteome
S Aretz, TU Krohne, K Kammerer, U Warnken, A Hotz-Wagenblatt, ...
Proteome science 11 (1), 1-10, 2013
Pathological but not physiological retinal neovascularization is altered in TNF-Rp55-receptor–deficient mice
N Kociok, S Radetzky, TU Krohne, C Gavranic, AM Joussen
Investigative ophthalmology & visual science 47 (11), 5057-5065, 2006
Complement component C5a primes retinal pigment epithelial cells for inflammasome activation by lipofuscin-mediated photooxidative damage
C Brandstetter, FG Holz, TU Krohne
Journal of Biological Chemistry 290 (52), 31189-31198, 2015
Growth suppression of the hepatocellular carcinoma cell line Hepa1-6 by an activatable interferon regulatory factor-1 in mice
A Kröger, D Ortmann, TU Krohne, L Mohr, HE Blum, H Hauser, ...
Cancer research 61 (6), 2609-2617, 2001
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