| Gene expression profiling predicts clinical outcome of breast cancer LJ Van't Veer, H Dai, MJ Van De Vijver, YD He, AAM Hart, M Mao, ... nature 415 (6871), 530-536, 2002 | 11986 | 2002 |
| A gene-expression signature as a predictor of survival in breast cancer MJ Van De Vijver, YD He, LJ Van't Veer, H Dai, AAM Hart, DW Voskuil, ... New England Journal of Medicine 347 (25), 1999-2009, 2002 | 7878 | 2002 |
| A system for stable expression of short interfering RNAs in mammalian cells TR Brummelkamp, R Bernards, R Agami science 296 (5567), 550-553, 2002 | 6856 | 2002 |
| The consensus molecular subtypes of colorectal cancer J Guinney, R Dienstmann, X Wang, A De Reynies, A Schlicker, ... Nature medicine 21 (11), 1350-1356, 2015 | 5139 | 2015 |
| A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma SH Friend, R Bernards, S Rogelj, RA Weinberg, JM Rapaport, DM Albert, ... Nature 323 (6089), 643-646, 1986 | 3893 | 1986 |
| Unresponsiveness of colon cancer to BRAF (V600E) inhibition through feedback activation of EGFR A Prahallad, C Sun, S Huang, F Di Nicolantonio, R Salazar, D Zecchin, ... Nature 483 (7387), 100-103, 2012 | 2303 | 2012 |
| A genomic and functional inventory of deubiquitinating enzymes SMB Nijman, MPA Luna-Vargas, A Velds, TR Brummelkamp, AMG Dirac, ... Cell 123 (5), 773-786, 2005 | 2237 | 2005 |
| 70-gene signature as an aid to treatment decisions in early-stage breast cancer F Cardoso, LJ van’t Veer, J Bogaerts, L Slaets, G Viale, S Delaloge, ... New England Journal of Medicine 375 (8), 717-729, 2016 | 2049 | 2016 |
| A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer K Berns, HM Horlings, BT Hennessy, M Madiredjo, EM Hijmans, K Beelen, ... Cancer cell 12 (4), 395-402, 2007 | 1945 | 2007 |
| Stable suppression of tumorigenicity by virus-mediated RNA interference TR Brummelkamp, R Bernards, R Agami Cancer cell 2 (3), 243-247, 2002 | 1717 | 2002 |
| A large-scale RNAi screen in human cells identifies new components of the p53 pathway K Berns, EM Hijmans, J Mullenders, TR Brummelkamp, A Velds, ... Nature 428 (6981), 431-437, 2004 | 1472 | 2004 |
| Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-κB TR Brummelkamp, SMB Nijman, AMG Dirac, R Bernards Nature 424 (6950), 797-801, 2003 | 1262 | 2003 |
| An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer K Stemke-Hale, AM Gonzalez-Angulo, A Lluch, RM Neve, WL Kuo, ... Cancer research 68 (15), 6084-6091, 2008 | 1237 | 2008 |
| Metastasis genes: a progression puzzle R Bernards, RA Weinberg Nature 418 (6900), 823-823, 2002 | 1089 | 2002 |
| Reversible and adaptive resistance to BRAF (V600E) inhibition in melanoma C Sun, L Wang, S Huang, GJJE Heynen, A Prahallad, C Robert, ... Nature 508 (7494), 118-122, 2014 | 944 | 2014 |
| CDK-independent activation of estrogen receptor by cyclin D1 RML Zwijsen, E Wientjens, R Klompmaker, J van der Sman, R Bernards, ... Cell 88 (3), 405-415, 1997 | 903 | 1997 |
| The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogene BD Rowland, R Bernards, DS Peeper Nature cell biology 7 (11), 1074-1082, 2005 | 759 | 2005 |
| Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence RM Kortlever, PJ Higgins, R Bernards Nature cell biology 8 (8), 877-884, 2006 | 734 | 2006 |
| Enabling personalized cancer medicine through analysis of gene-expression patterns LJ Van't Veer, R Bernards Nature 452 (7187), 564-570, 2008 | 718 | 2008 |
| The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway SMB Nijman, TT Huang, AMG Dirac, TR Brummelkamp, RM Kerkhoven, ... Molecular cell 17 (3), 331-339, 2005 | 702 | 2005 |
Lodewyk WesselsProfessor of Computational Cancer BiologyBestätigte E-Mail-Adresse bei nki.nl
