Highly selective phosphatidylinositol 4-kinase IIIβ inhibitors and structural insight into their mode of action I Mejdrová, D Chalupská, M Kögler, M Šála, P Plačková, A Baumlová, ... Journal of medicinal chemistry 58 (9), 3767-3793, 2015 | 67 | 2015 |
Rational design of novel highly potent and selective phosphatidylinositol 4-kinase IIIβ (PI4KB) inhibitors as broad-spectrum antiviral agents and tools for chemical biology I Mejdrová, D Chalupská, P Plačková, C Müller, M Šála, M Klíma, ... Journal of medicinal chemistry 60 (1), 100-118, 2017 | 53 | 2017 |
Uncovering key structural features of an enantioselective peptide‐catalyzed acylation utilizing advanced NMR techniques E Procházková, A Kolmer, J Ilgen, M Schwab, L Kaltschnee, ... Angewandte Chemie International Edition 55 (51), 15754-15759, 2016 | 51 | 2016 |
Microwave-assisted hydrolysis of phosphonate diesters: an efficient protocol for the preparation of phosphonic acids P Jansa, O Baszczyňski, E Procházková, M Dračínský, Z Janeba Green Chemistry 14 (8), 2282-2288, 2012 | 50 | 2012 |
Resolution of organic polymorphic crystals by raman spectroscopy M Dračínský, E Procházková, J Kessler, J Šebestík, P Matějka, ... The Journal of Physical Chemistry B 117 (24), 7297-7307, 2013 | 37 | 2013 |
Novel human neutral sphingomyelinase 2 inhibitors as potential therapeutics for Alzheimer’s disease M Šála, KR Hollinger, AG Thomas, RP Dash, C Tallon, V Veeravalli, ... Journal of medicinal chemistry 63 (11), 6028-6056, 2020 | 36 | 2020 |
Reactive cyclic intermediates in the ProTide prodrugs activation: trapping the elusive pentavalent phosphorane E Procházková, R Navrátil, Z Janeba, J Roithová, O Baszczyňski Organic & biomolecular chemistry 17 (2), 315-320, 2019 | 30 | 2019 |
Photoswitchable Intramolecular Hydrogen Bonds in 5‐Phenylazopyrimidines Revealed By In Situ Irradiation NMR Spectroscopy E Procházková, L Čechová, J Kind, Z Janeba, CM Thiele, M Dračínský Chemistry–A European Journal 24 (2), 492-498, 2018 | 30 | 2018 |
Synthesis and Evaluation of Novel Acyclic Nucleoside Phosphonates as Inhibitors of Plasmodium falciparum and Human 6‐Oxopurine Phosphoribosyltransferases MM Kaiser, D Hocková, TH Wang, M Dračínský, L Poštová‐Slavětínská, ... ChemMedChem 10 (10), 1707-1723, 2015 | 25 | 2015 |
Norbornane-based nucleoside and nucleotide analogues locked in North conformation M Dejmek, M Šála, H Hřebabecký, M Dračínský, E Procházková, ... Bioorganic & Medicinal Chemistry 23 (1), 184-191, 2015 | 24 | 2015 |
Photoswitching behavior of 5-phenylazopyrimidines: in situ irradiation NMR and optical spectroscopy combined with theoretical methods L Čechová, J Kind, M Dracinsky, J Filo, Z Janeba, CM Thiele, M Cigáň, ... The Journal of Organic Chemistry 83 (11), 5986-5998, 2018 | 23 | 2018 |
Resonance-assisted stabilisation of hydrogen bonds probed by NMR spectroscopy and path integral molecular dynamics M Dračínský, L Čechová, P Hodgkinson, E Procházková, Z Janeba Chemical communications 51 (73), 13986-13989, 2015 | 23 | 2015 |
A switchable intramolecular hydrogen bond in polysubstituted 5-nitrosopyrimidines E Prochazkova, L Cechova, Z Janeba, M Dracinsky The Journal of Organic Chemistry 78 (20), 10121-10133, 2013 | 20 | 2013 |
Purine analogs as phosphatidylinositol 4-kinase IIIβ inhibitors M Šála, M Kögler, P Plačková, I Mejdrová, H Hřebabecký, E Procházková, ... Bioorganic & Medicinal Chemistry Letters 26 (11), 2706-2712, 2016 | 19 | 2016 |
Polymorphic transformation of drugs induced by glycopolymeric vesicles designed for anticancer therapy probed by solid-state NMR spectroscopy E Prochazkova, C Cao, A Rawal, M Dracinsky, S Bhattacharyya, ... ACS applied materials & interfaces 11 (31), 28278-28288, 2019 | 18 | 2019 |
From norbornane-based nucleotide analogs locked in South conformation to novel inhibitors of feline herpes virus M Dejmek, H Hřebabecký, M Šála, M Dračínský, E Procházková, ... Bioorganic & Medicinal Chemistry 22 (11), 2974-2983, 2014 | 18 | 2014 |
Influence of intramolecular charge transfer and nuclear quantum effects on intramolecular hydrogen bonds in azopyrimidines K Bartova, L Cechova, E Prochazkova, O Socha, Z Janeba, M Dracinsky The Journal of Organic Chemistry 82 (19), 10350-10359, 2017 | 17 | 2017 |
Polysubstituted 5‐Phenylazopyrimidines: Extremely Fast Non‐ionic Photochromic Oscillators L Čechová, J Filo, M Dračínský, C Slavov, D Sun, Z Janeba, T Slanina, ... Angewandte Chemie 132 (36), 15720-15724, 2020 | 16 | 2020 |
Separation of planar rotamers through intramolecular hydrogen bonding in polysubstituted 5-nitrosopyrimidines L Čechová, E Procházková, I Císařová, M Dračínský, Z Janeba Chemical communications 50 (94), 14892-14895, 2014 | 14 | 2014 |
Tunable push–pull interactions in 5-nitrosopyrimidines E Procházková, L Čechová, J Tarábek, Z Janeba, M Dračínský The Journal of Organic Chemistry 81 (9), 3780-3789, 2016 | 13 | 2016 |