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Charu Mehta
Charu Mehta
Postdoctoral fellow
Verified email at fredhutch.org - Homepage
Title
Cited by
Cited by
Year
The GATA factor revolution in hematology
KR Katsumura, EH Bresnick, GATA Factor Mechanisms Group
Blood, The Journal of the American Society of Hematology 129 (15), 2092-2102, 2017
1492017
Integrating enhancer mechanisms to establish a hierarchical blood development program
C Mehta, KD Johnson, X Gao, IM Ong, KR Katsumura, SC McIver, ...
Cell reports 20 (12), 2966-2979, 2017
572017
Single-nucleotide human disease mutation inactivates a blood-regenerative GATA2 enhancer
AA Soukup, Y Zheng, C Mehta, J Wu, P Liu, M Cao, I Hofmann, Y Zhou, ...
The Journal of clinical investigation 129 (3), 1180-1192, 2019
532019
Human leukemia mutations corrupt but do not abrogate GATA-2 function
KR Katsumura, C Mehta, KJ Hewitt, AA Soukup, I Fraga de Andrade, ...
Proceedings of the National Academy of Sciences 115 (43), E10109-E10118, 2018
422018
Mechanisms of erythrocyte development and regeneration: implications for regenerative medicine and beyond
EH Bresnick, KJ Hewitt, C Mehta, S Keles, RF Paulson, KD Johnson
Development 145 (1), dev151423, 2018
382018
Post-transcriptional control of cellular differentiation by the RNA exosome complex
I Fraga de Andrade, C Mehta, EH Bresnick
Nucleic Acids Research 48 (21), 11913-11928, 2020
272020
Synthetic genome readers target clustered binding sites across diverse chromatin states
GS Erwin, MP Grieshop, D Bhimsaria, TJ Do, JA Rodríguez-Martínez, ...
Proceedings of the National Academy of Sciences 113 (47), E7418-E7427, 2016
202016
Dissecting regulatory mechanisms using mouse fetal liver-derived erythroid cells
SC McIver, KJ Hewitt, X Gao, C Mehta, J Zhang, EH Bresnick
Erythropoiesis: Methods and Protocols, 67-89, 2018
172018
GATA factor-regulated solute carrier ensemble reveals a nucleoside transporter-dependent differentiation mechanism
NM Zwifelhofer, X Cai, R Liao, B Mao, DJ Conn, C Mehta, S Keles, Y Xia, ...
PLoS Genetics 16 (12), e1009286, 2020
162020
Breaking the spatial constraint between neighboring zinc fingers: a new germline mutation in GATA2 deficiency syndrome
M Cavalcante de Andrade Silva, KR Katsumura, C Mehta, EDRP Velloso, ...
Leukemia 35 (1), 264-268, 2021
142021
RNA-regulatory exosome complex confers cellular survival to promote erythropoiesis
C Mehta, I Fraga de Andrade, DR Matson, CN Dewey, EH Bresnick
Nucleic Acids Research 49 (16), 9007-9025, 2021
92021
Gata2 −77 enhancer regulates adult hematopoietic stem cell survival
X You, YI Chang, G Kong, EA Ranheim, Y Zhou, KD Johnson, C Mehta, ...
Leukemia 35 (3), 901-905, 2021
72021
RNA-regulatory exosome complex suppresses an apoptotic program to confer erythroid progenitor cell survival in vivo
I Fraga de Andrade, KD Johnson, C Mehta, CN Dewey, U Basu, ...
Blood Advances 7 (4), 586-601, 2023
12023
Single-Nucleotide Human Disease Mutation Inactivates a Blood-Regenerative Enhancer
A Soukup, C Mehta, P Liu, M Cao, I Hofmann, Y Zhou, J Zhang, K Choi, ...
Blood, The Journal of the American Society of Hematology 132 (Supplement 1 …, 2018
12018
Pathogenic GATA2 genetic variants utilize an obligate enhancer mechanism to distort a multilineage differentiation program
KR Katsumura, P Liu, J Kim, C Mehta, EH Bresnick
Proceedings of the National Academy of Sciences 121 (10), e2317147121, 2024
2024
GATA Factor Mechanisms in Erythrocyte Development
C Mehta
The University of Wisconsin-Madison, 2021
2021
Loss-of-Function and Gain-of-Function Consequences of GATA2 Disease Mutations
KR Katsumura, P Liu, C Mehta, KJ Hewitt, A Soukup, IJF de Andrade, ...
Blood 134, 2519, 2019
2019
Elucidating an Erythroblast Survival Mechanism: Differential Contributions of Exosome Complex Catalytic Subunits
C Mehta, IJF de Andrade, N Tanimura, GM Wilson, EA Ranheim, JJ Coon, ...
Blood 134, 155, 2019
2019
GATA-2 Dependent Hematologic Disease Mechanism
A Soukup, K Johnson, C Mehta, Y Zhou, J Zhang, E Bresnick
Experimental Hematology 64, S45, 2018
2018
Enhancer mechanisms governing developmental and regenerative hematopoietic programs
E Bresnick, K Hewitt, C Mehta, K Johnson, D Matson, K Katsumura, X Gao, ...
Experimental Hematology 53, S28, 2017
2017
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