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Ignacio Leon
Ignacio Leon
Investigador de la Facultad de Ciencias Exactas, Universidad Nacional de La Plata
Verified email at biol.unlp.edu.ar - Homepage
Title
Cited by
Cited by
Year
Vanadium and cancer treatment: antitumoral mechanisms of three oxidovanadium (IV) complexes on a human osteosarcoma cell line
IE Leon, N Butenko, AL Di Virgilio, CI Muglia, EJ Baran, I Cavaco, ...
Journal of inorganic biochemistry 134, 106-117, 2014
972014
Antitumor properties of a vanadyl (IV) complex with the flavonoid chrysin [VO (chrysin) 2 EtOH] 2 in a human osteosarcoma model: the role of oxidative stress and apoptosis
IE Leon, AL Di Virgilio, V Porro, CI Muglia, LG Naso, PAM Williams, ...
Dalton Transactions 42 (33), 11868-11880, 2013
892013
Oxidovanadium (IV) complexes with chrysin and silibinin: anticancer activity and mechanisms of action in a human colon adenocarcinoma model
IE Leon, JF Cadavid-Vargas, I Tiscornia, V Porro, S Castelli, P Katkar, ...
JBIC Journal of Biological Inorganic Chemistry 20, 1175-1191, 2015
842015
Modified bacterial cellulose scaffolds for localized doxorubicin release in human colorectal HT-29 cells
ML Cacicedo, IE León, JS Gonzalez, LM Porto, VA Alvarez, GR Castro
Colloids and Surfaces B: Biointerfaces 140, 421-429, 2016
722016
Bacterial cellulose hydrogel loaded with lipid nanoparticles for localized cancer treatment
ML Cacicedo, GA Islan, IE León, VA Alvarez, I Chourpa, E Allard-Vannier, ...
Colloids and surfaces B: Biointerfaces 170, 596-608, 2018
712018
Antiproliferative and apoptosis-inducing activity of an oxidovanadium (IV) complex with the flavonoid silibinin against osteosarcoma cells
IE Leon, V Porro, AL Di Virgilio, LG Naso, PAM Williams, M Bollati-Fogolín, ...
JBIC Journal of Biological Inorganic Chemistry 19, 59-74, 2014
642014
Synthesis and characterization of CaCO3–biopolymer hybrid nanoporous microparticles for controlled release of doxorubicin
VE Bosio, ML Cacicedo, B Calvignac, I León, T Beuvier, F Boury, ...
Colloids and Surfaces B: Biointerfaces 123, 158-169, 2014
622014
In vitro and in vivo antitumor effects of the VO-chrysin complex on a new three-dimensional osteosarcoma spheroids model and a xenograft tumor in mice
IE León, JF Cadavid-Vargas, A Resasco, F Maschi, MA Ayala, C Carbone, ...
JBIC Journal of Biological Inorganic Chemistry 21, 1009-1020, 2016
552016
Synthesis, crystal structure and cytotoxicity assays of a copper (II) nitrate complex with a tridentate ONO acylhydrazone ligand. Spectroscopic and theoretical studies of the …
Y Burgos-Lopez, J Del Plá, LM Balsa, IE León, GA Echeverría, OE Piro, ...
Inorganica Chimica Acta 487, 31-40, 2019
502019
Polyoxometalates as antitumor agents: bioactivity of a new polyoxometalate with copper on a human osteosarcoma model
IE Leon, V Porro, S Astrada, MG Egusquiza, CI Cabello, M Bollati-Fogolin, ...
Chemico-biological interactions 222, 87-96, 2014
492014
Anticancer and antimetastatic activity of copper (II)-tropolone complex against human breast cancer cells, breast multicellular spheroids and mammospheres
LM Balsa, MC Ruiz, LSM de la Parra, EJ Baran, IE León
Journal of Inorganic Biochemistry 204, 110975, 2020
452020
Mononuclear Pd (ii) and Pt (ii) complexes with an α-N-heterocyclic thiosemicarbazone: cytotoxicity, solution behaviour and interaction versus proven models from biological media
AI Matesanz, E Jimenez-Faraco, MC Ruiz, LM Balsa, ...
Inorganic Chemistry Frontiers 5 (1), 73-83, 2018
442018
Deciphering the effect of an oxovanadium(iv) complex with the flavonoid chrysin (VOChrys) on intracellular cell signalling pathways in an osteosarcoma cell line
IE León, P Díez, SB Etcheverry, M Fuentes
Metallomics 8 (8), 739-749, 2016
442016
Comparative antitumor studies of organoruthenium complexes with 8-hydroxyquinolines on 2D and 3D cell models of bone, lung and breast cancer
MC Ruiz, J Kljun, I Turel, AL Di Virgilio, IE León
Metallomics 11 (3), 666-675, 2019
422019
Synthesis and biological characterization of organoruthenium complexes with 8-hydroxyquinolines
J Kljun, IE León, Š Peršič, JF Cadavid-Vargas, SB Etcheverry, W He, ...
Journal of Inorganic Biochemistry 186, 187-196, 2018
422018
Tetracycline-resistance encoding plasmids from Paenibacillus larvae, the causal agent of American foulbrood disease, isolated from commercial honeys
AM Alippi, IE Leon, AC López
Viguera Editores, 2014
372014
In vitro and in vivo anticancer effects of two quinoline–platinum (II) complexes on human osteosarcoma models
MC Ruiz, A Resasco, AL Di Virgilio, M Ayala, I Cavaco, S Cabrera, ...
Cancer Chemotherapy and Pharmacology 83, 681-692, 2019
322019
Anticancer activity of a new copper (ii) complex with a hydrazone ligand. Structural and spectroscopic characterization, computational simulations and cell mechanistic studies …
LM Balsa, V Ferraresi-Curotto, MJ Lavecchia, GA Echeverría, OE Piro, ...
Dalton Transactions 50 (28), 9812-9826, 2021
302021
Decoding the anticancer activity of VO-clioquinol compound: the mechanism of action and cell death pathways in human osteosarcoma cells
IE León, P Díez, EJ Baran, SB Etcheverry, M Fuentes
Metallomics 9 (7), 891-901, 2017
292017
Design of nalidixic acid‑vanadium complex loaded into chitosan hybrid nanoparticles as smart strategy to inhibit bacterial growth and quorum sensing
B Bueloni, D Sanna, E Garribba, GR Castro, IE León, GA Islan
International Journal of Biological Macromolecules 161, 1568-1580, 2020
282020
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